Surveillance of penicillin resistance of Neisseria meningitidis strains from invasive infections between 2013 and 2018 in Turkey.

Autor: Karadag Oncel E; Clinics of Pediatric Infectious Diseases, SBU Izmir Tepecik Research and Training Hospital, İzmir, Turkey., Ceyhan M; Department of Pediatric Infectious Diseases, Hacettepe University School of Medicine, Ankara, Turkey., Tanir Basaranoglu S; Department of Pediatric Infectious Diseases, Hacettepe University School of Medicine, Ankara, Turkey., Gurbuz V; Department of Pediatric Infectious Diseases, Hacettepe University School of Medicine, Ankara, Turkey., Aycan AE; Department of Pediatric Infectious Diseases, Hacettepe University School of Medicine, Ankara, Turkey., Ozsurekci Y; Department of Pediatric Infectious Diseases, Hacettepe University School of Medicine, Ankara, Turkey., Kurugol Z; Department of Pediatric Infectious Diseases, Ege University School of Medicine, Izmir, Turkey., Keser Emiroglu M; Department of Pediatric Infectious Diseases, Selçuk University Faculty of Medicine, Konya, Turkey., Devrim I; Department of Pediatric Infectious Diseases, Dr. Behçet Uz Children's Hospital, Izmir, Turkey., Karbuz A; Clinics of Pediatric Infectious Diseases, Okmeydanı Training and Research Hospital, Istanbul, Turkey., Altay Akisoglu HO; Department of Microbiology, Dr. Sami Ulus Maternity and Children's Training and Research Hospital, Ankara, Turkey., Gurler N; Department of Medical Microbiology, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey.
Jazyk: angličtina
Zdroj: Journal of chemotherapy (Florence, Italy) [J Chemother] 2020 Jul; Vol. 32 (4), pp. 213-216. Date of Electronic Publication: 2020 Feb 07.
DOI: 10.1080/1120009X.2020.1721176
Abstrakt: Neisseria meningitidis ( N. meningitidis ) is regarded as the leading cause of bacterial meningitis in many regions of the world. The empiric antimicrobial treatment is mainly based on antimicrobial resistance and patient characteristics. We aimed to analyze susceptibility patterns of N. meningitidis strains isolated in Turkey. Invasive meningococci collected in a multicenter, hospital-based, epidemiological surveillance study of pediatric (0-18 years of age) bacterial meningitis cases between 2013 and 2018 were studied. Five isolates (8.7%) displayed resistance to penicillin-G, while 13 isolates (22.8%) had intermediate susceptibility. All isolates were cefotaxime and rifampin susceptible. The data shows appropriateness of third-generation cephalosporins in empirical use for meningococcal infections in children. Since Turkey is located in a transition zone geographically, surveillance reports are very crucial.
Databáze: MEDLINE
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