Alcohol Makes Its Epigenetic Marks.
| Autor: | Pandey SC; Center for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA; Jesse Brown VA Medical Center, Chicago, IL 60612, USA. Electronic address: scpandey@uic.edu., Bohnsack JP; Center for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Cell metabolism [Cell Metab] 2020 Feb 04; Vol. 31 (2), pp. 213-214. |
| DOI: | 10.1016/j.cmet.2020.01.008 |
| Abstrakt: | The toxic effects of alcohol consumption are dependent upon its metabolism in the liver to downstream metabolites: acetaldehyde, acetate, and acetyl-CoA. Recently, in Nature, Mews et al. (2019) have discovered that acetyl-CoA derived from alcohol plays an important epigenetic role in regulating ethanol's effects on the brain through histone acetylation. (Published by Elsevier Inc.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|