New Insights on Pulmonary Paracoccidioidomycosis.

Autor: Queiroz-Telles FV; Department of Public Health, Hospital de Clínicas, Federal University of Parana, Parana, Brazil., Peçanha Pietrobom PM; Division of Infectious Diseases, Department of Medicine, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo, Brazil., Rosa Júnior M; Section of Radiology, Department of Medicine, Hospital Universitário Cassiano Antônio de Moraes, Federal University of Espírito Santo, Espírito Santo, Brazil., Baptista RM; Section of Radiology, Department of Medicine, Hospital Universitário Cassiano Antônio de Moraes, Federal University of Espírito Santo, Espírito Santo, Brazil., Peçanha PM; Section of Infectious Diseases, Department of Medicine, Hospital Universitário Cassiano Antônio de Moraes, Federal University of Espírito Santo, Espírito Santo, Brazil.
Jazyk: angličtina
Zdroj: Seminars in respiratory and critical care medicine [Semin Respir Crit Care Med] 2020 Feb; Vol. 41 (1), pp. 53-68. Date of Electronic Publication: 2020 Jan 30.
DOI: 10.1055/s-0039-3400544
Abstrakt: Paracoccidioidomycosis (PCM) is one of the most relevant systemic endemic mycoses in Latin American countries, especially in South American countries, with endemic and hyperendemic areas. The real burden of PCM may be underestimated because of a lack of compulsory case notification. Recent phylogenetic data revealed that Paracoccidioides brasiliensis comprises several cryptic species including P. brasiliensis and P. lutzii . However, the genetic biodiversity of Paracoccidioides does not affect the clinical manifestations or therapeutic response to therapy. Lung involvement is a common finding, especially in patients experiencing the chronic form of the disease, and, because of its similarities with tuberculosis, clinicians must be alert to the possibility of PCM in patients with chronic respiratory manifestations and epidemiological risk factors for this fungal disease.
Competing Interests: None.
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Databáze: MEDLINE