Pulmonary Coccidioidomycosis.
| Autor: | Kimes KE; Division of Infectious Diseases, Mayo Clinic Hospital, Phoenix, Arizona., Kasule SN; Department of Internal Medicine, Mayo Clinic, Scottsdale, Arizona., Blair JE; Division of Infectious Diseases, Mayo Clinic Hospital, Phoenix, Arizona. |
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| Jazyk: | angličtina |
| Zdroj: | Seminars in respiratory and critical care medicine [Semin Respir Crit Care Med] 2020 Feb; Vol. 41 (1), pp. 42-52. Date of Electronic Publication: 2020 Jan 30. |
| DOI: | 10.1055/s-0039-3400998 |
| Abstrakt: | Coccidioidomycosis is an infection caused by the geographically restricted dimorphic fungus, Coccidioides . Coccidioidomycosis occurs endemically in the southwestern and western United States, mainly in focused regions of Arizona and California where the incidence is highest, and in Central and South America. Patients with impaired immunity, especially those with impaired cellular immunity, are at higher risk of severe and disseminated disease. In this review, we describe the fungal ecology and mycology, epidemiology, pathophysiology, and normal immune defenses to Coccidioides as well as address current concepts in diagnosis, treatment, and continued care of patients with pulmonary coccidioidomycosis. We also present and answer our most frequently asked questions regarding patients with primary pulmonary coccidioidomycosis. Competing Interests: No conflict of interest to disclose. (Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.) |
| Databáze: | MEDLINE |
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