Detection of perilymphatic fistula in labyrinthine windows by virtual endoscopy and variation of reconstruction thresholds on CT scan.

Autor: Bozorg Grayeli A; Department of Otolaryngology, Dijon University Hospital, Université Bourgogne-Franche Comté, Dijon, France.; Le2i Research Laboratory, CNRS UMR 6306, Université Bourgogne-Franche Comté, Dijon, France., Bensimon JL; Imaging Center, Clinique Turin, Paris, France., Guyon M; Department of Otolaryngology, Dijon University Hospital, Université Bourgogne-Franche Comté, Dijon, France.; Le2i Research Laboratory, CNRS UMR 6306, Université Bourgogne-Franche Comté, Dijon, France., Aho-Glele S; Department of Epidemiology, Dijon University Hospital, Université Bourgogne-Franche Comté, Dijon, France., Toupet M; Department of Otolaryngology, Dijon University Hospital, Université Bourgogne-Franche Comté, Dijon, France.; Centre d'Explorations Fonctionnelles Otoneurologiques, Paris, France.
Jazyk: angličtina
Zdroj: Acta oto-laryngologica [Acta Otolaryngol] 2020 Apr; Vol. 140 (4), pp. 270-276. Date of Electronic Publication: 2020 Jan 29.
DOI: 10.1080/00016489.2020.1715472
Abstrakt: Background: Perilymphatic fistula (PLF) is a breach in a labyrinthine window. The opening might decrease the radiological density of the window. Aims/objectives: To evaluate the radiological density of the labyrinthine windows by virtual endoscopy on CT scan. Materials and methods: This prospective study included 47 adult patients with PLF and 98 control patients. Diagnosis of PLF was based on a composite radio clinical score and/or intra operative visualization of the fistula and/or resolution of the symptoms after surgery. On routine CT-scan, labyrinthine windows were examined by virtual endoscopy. The reconstruction threshold was gradually increased until a virtual opening appeared (opening threshold [OT]) and compared to the contralateral window (OT difference). Results: The OT difference was higher in patients than in controls (60.2 ± 10.36 (SEM), n  = 47 versus 28.0 ± 2.29 Hounsfield units (HUs), n  = 98, p  < .01 unpaired t -test). A ROC analysis showed that at an OT difference of 31.5 UH had a sensitivity of 75% and a specificity of 75% for the PLF diagnosis. Conclusions: CT-scan virtual endoscopy and threshold variation provided high specificity and sensitivity in the PLF diagnosis. Significance: This post processing of radiological data appears to enhance the diagnostic value of CT scan.
Databáze: MEDLINE
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