In vitro characterization of virulence factors among species of the Candida parapsilosis complex.

Autor:	Ataides FS; Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brasil., Costa CR; Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brasil., Santos AS; Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brasil., Freitas VAQ; Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brasil., Silva TC; Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brasil., Zara ALSA; Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brasil., Jesuino RSA; Universidade Federal de Goiás, Instituto de Ciências Biológicas II, Goiânia, GO, Brasil., Silva MRR; Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brasil.
Jazyk:	angličtina
Zdroj:	Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2020 Jan 27; Vol. 53, pp. e20190336. Date of Electronic Publication: 2020 Jan 27 (Print Publication: 2020).
DOI:	10.1590/0037-8682-0336-2019
Abstrakt:	Introduction: Candida parapsilosis complex species differ from each other with regard to their prevalence and virulence. Methods: The hydrolytic enzyme activity, biofilm production, and adhesion to epithelial cells were analyzed in 87 C. parapsilosis complex strains. Results: Among the studied isolates, 97.7%, 63.2%, and 82.8% exhibited very strong proteinase, esterase, and hemolysin activity, respectively. All the C. parapsilosis complex isolates produced biofilms and presented an average adherence of 96.0 yeasts/100 epithelial cells. Conclusions: Our results show that Candida parapsilosis complex isolates showed different levels of enzyme activity, biofilm production, and adhesion to epithelial cells.
Databáze:	MEDLINE
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