An adolescent case of extensive Behçet`s disease successfully treated with Infliximab.

Autor: Isıyel E; Divisions of Pediatric Nephrology, Gazi University Faculty of Medicine, Ankara, Turkey., Bakkaloğlu S; Divisions of Pediatric Nephrology, Gazi University Faculty of Medicine, Ankara, Turkey., Oğuz D; Department of Pediatric Cardiology, Gazi University Faculty of Medicine, Ankara, Turkey., Yenicesu İ; Department of Pediatric Hematology, Gazi University Faculty of Medicine, Ankara, Turkey., Boyunağa Ö; Department of Radiology, Gazi University Faculty of Medicine, Ankara, Turkey., Özdemir Y; Divisions of Pediatric Nephrology, Gazi University Faculty of Medicine, Ankara, Turkey., Damar Ç; Department of Radiology, Gazi University Faculty of Medicine, Ankara, Turkey., Kandur Y; Divisions of Pediatric Nephrology, Gazi University Faculty of Medicine, Ankara, Turkey., Akçaboy M; Divisions of Pediatric Nephrology, Gazi University Faculty of Medicine, Ankara, Turkey., Aslan AT; Department of Pediatric Pulmonology, Department of Pediatrics; Gazi University Faculty of Medicine, Ankara, Turkey., Şişmanlar T; Department of Pediatric Pulmonology, Department of Pediatrics; Gazi University Faculty of Medicine, Ankara, Turkey., Hasanoğlu E; Divisions of Pediatric Nephrology, Gazi University Faculty of Medicine, Ankara, Turkey., Buyan N; Divisions of Pediatric Nephrology, Gazi University Faculty of Medicine, Ankara, Turkey.
Jazyk: angličtina
Zdroj: The Turkish journal of pediatrics [Turk J Pediatr] 2019; Vol. 61 (4), pp. 585-588.
DOI: 10.24953/turkjped.2019.04.016
Abstrakt: Isıyel E, Bakkaloğlu S, Oğuz D, Yenicesu İ, Boyunağa Ö, Özdemir Y, Damar Ç, Kandur Y, Akçaboy M, Aslan AT, Şişmanlar T, Hasanoğlan E, Buyan N. An adolescent case of extensive Behçet`s disease successfully treated with Infliximab. Turk J Pediatr 2019; 61: 585-588. Cardiac involvement is an uncommon and life-threatening complication of Behçet`s Disease. We present a 14-year-old boy, admitted to our hospital for recurrent hemoptysis. In his radiologic evaluation, a right ventricular thrombus and pulmonary arterial aneurysm were identified. He was diagnosed with Behçet`s Disease, and then he received prednisone and cyclophosphamide. However, his cardiac thrombus enlargened. After his treatment was replaced with infliximab, the pulmonary aneurysms regressed, and the cardiac thrombus disappeared. In conclusion, infliximab should be considered as a reliable option for vascular Behçet`s Disease resistant to conventional treatment.
Databáze: MEDLINE