A Low 50-gram, 1-hour Glucose Challenge Test Value Predicts Neonatal Birth Weight Less than the 10th Percentile: A Systematic Review and Meta-Analysis.

Autor:	Mitta M; Department of Obstetrics and Gynecology, University of Florida College of Medicine, Jacksonville, Florida., Sanchez-Ramos L; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Florida College of Medicine, Jacksonville, Florida., Roeckner JT; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Florida College of Medicine, Jacksonville, Florida., Bennett S; Department of Obstetrics and Gynecology, University of Florida College of Medicine, Jacksonville, Florida., Kovacs A; Department of Obstetrics and Gynecology, University of Florida College of Medicine, Jacksonville, Florida., Kaunitz AM; Department of Obstetrics and Gynecology, University of Florida College of Medicine, Jacksonville, Florida.
Jazyk:	angličtina
Zdroj:	American journal of perinatology [Am J Perinatol] 2021 Jul; Vol. 38 (8), pp. 841-847. Date of Electronic Publication: 2020 Jan 27.
DOI:	10.1055/s-0039-3402749
Abstrakt:	Objective: This study aimed to perform a systematic review with meta-analysis to investigate if women with a low 50-g, 1-hour glucose challenge test (GCT) value are at risk for having neonates with a birth weight less than the 10th percentile. Study Design: A computerized literature search was conducted to identify studies that compared outcomes of pregnant women with a low GCT value versus women with a normal GCT value during routine screening for gestational diabetes. Results: Sixteen cohort studies were included for analysis. Women with a low GCT value were noted to have a 43% increased odds of having neonates with birth weight less than the 10th percentile (odds ratio [OR]: 1.43; 95% confidence interval [CI]: 1.28-1.60) and 30% increased odds of having neonates with a birth weight less than 2,500 g (OR: 1.3; 95% CI: 1.0-1.7) when compared with women with a normal GCT value. The rates of preterm delivery, neonatal intensive care unit (NICU) admission, pregnancy-induced hypertension (PIH)/preeclampsia, respiratory distress, NICU, and Apgar scores less than 7 were similar in the two groups. Conclusion: A low GCT value defined as less than 90 mg/dL identifies pregnancies at elevated risk for having neonates with a birth weight less than the 10th percentile. Competing Interests: None declared. (Thieme. All rights reserved.)
Databáze:	MEDLINE
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