The correlation between lncRNAs and Helicobacter pylori in gastric cancer.

Autor:	Dastmalchi N; Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran., Khojasteh SMB; Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran., Nargesi MM; Department of Diagnostic Genetics, LabPLUS, Auckland City Hospital, Auckland District Health Board (ADHB), Auckland, New Zealand., Safaralizadeh R; Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Jazyk:	angličtina
Zdroj:	Pathogens and disease [Pathog Dis] 2019 Dec 01; Vol. 77 (9).
DOI:	10.1093/femspd/ftaa004
Abstrakt:	Helicobacter pylori infection performs a key role in gastric tumorigenesis. Long non-coding RNAs (lncRNAs) have demonstrated a great potential to be regarded as effective malignancy biomarkers for various gastrointestinal diseases including gastric cancer (GC). The present review highlights the relationship between lncRNAs and H. pylori in GC. Several studies have examined not only the involvement of lncRNAs in H. pylori-associated GC progression but also their molecular mechanisms of action. Among the pertinent studies, some have addressed the effects of H. pylori infection on modulatory networks of lncRNAs, while others have evaluated the effects of changes in the expression level of lncRNAs in H. pylori-associated gastric diseases, especially GC. The relationship between lncRNAs and H. pylori was found to be modulated by various molecular pathways. (© FEMS 2020.)
Databáze:	MEDLINE
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