Grading of Ultrasonography in Rheumatoid Arthritis of Wrist and Hand Joints.

Autor: Seifeldein GS; Diagnostic and Interventional Radiology Department, Assiut University, Faculty of Medicine, Assiut, 71515, Egypt. Electronic address: gehanseifeldein@aun.edu.eg., Moussa DK; Diagnostic and Interventional Radiology Department, Assiut University, Faculty of Medicine, Assiut, 71515, Egypt., Galal MAA; Rheumatology and Rehabilitation Department, Assiut University, Egypt., Othman MHM; Diagnostic and Interventional Radiology Department, Assiut University, Faculty of Medicine, Assiut, 71515, Egypt., El-Malah HEM; Diagnostic and Interventional Radiology Department, Assiut University, Faculty of Medicine, Assiut, 71515, Egypt.
Jazyk: angličtina
Zdroj: Academic radiology [Acad Radiol] 2020 Jul; Vol. 27 (7), pp. 937-943. Date of Electronic Publication: 2020 Jan 21.
DOI: 10.1016/j.acra.2019.09.033
Abstrakt: Rationale and Objectives: To evaluate the role of musculoskeletal ultrasound (MSUS) in the grading of rheumatoid arthritis (RA) wrist and hand joints and correlate it with clinical, laboratory, and radiological data.
Materials and Methods: A cross-sectional study recruited 50 patients in a tertiary care hospital. RA activity was assessed by DAS28. MSUS dorsal longitudinal scan was performed on the wrists, MCPs, and PIPS joints using high frequency (18 MHZ) linear transducer. 100 wrists in three different views, 500 MCPs, 500 PIPs were evaluated using the grayscale ultrasound and power Doppler ultrasound semiquantitative scale and scores ranging from 0-3. The results were correlated with clinical, laboratory and radiological data. All patients' wrist and hand joints X-rays were evaluated using the Larsen score.
Results: The mean age of the patients (49 females and one male) was 44.58 ± 10.07 years, and their mean disease duration was 16.26 ± 1.07 years. The mean DAS28 was 5.19 ± 0.95. 97.5% of joints had grade I Larsen score, 11.07% of the joints had erosions, 9.2% of the joints had effusions, 23.8% of the joints had synovial thickening, 11.9% of the joints showed PD signals and 3.5% of the joints were accompanied with tenosynovitis. Significant relations (p < 0.05) found among DAS28 and (PD signals, synovial thickening, tenosynovitis, effusion, and Larsen score). A nonsignificant relation (p > 0.05) among DAS28 and erosions detected by MSUS and X-ray.
Conclusion: MSUS is powerful in the detection of early RA regarding synovitis, joint effusion, tenosynovitis, and bone erosions, which were correlated with clinical and laboratory parameters.
(Copyright © 2019 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE