Co-occurrence of DNMT3A, NPM1, FLT3 mutations identifies a subset of acute myeloid leukemia with adverse prognosis.

Autor: Bezerra MF; Keizo Asami Immunopathology Laboratory, Federal University of Pernambuco, Recife, Brazil.; Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife, Brazil., Lima AS; Department of Genetics, Federal University of Pernambuco, Recife, Brazil., Piqué-Borràs MR; Department of Biomedicine, University of Basel, Basel, Switzerland., Silveira DR; Hematology Division, LIM31, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.; Hematology Department, AC Camargo Cancer Center, São Paulo, Brazil., Coelho-Silva JL; Department of Genetics, Federal University of Pernambuco, Recife, Brazil.; Department of Internal Medicine, Medical School of Ribeirão Preto, Ribeirão Preto, Brazil., Pereira-Martins DA; Department of Genetics, Federal University of Pernambuco, Recife, Brazil.; Department of Internal Medicine, Medical School of Ribeirão Preto, Ribeirão Preto, Brazil., Weinhäuser I; Department of Internal Medicine, Medical School of Ribeirão Preto, Ribeirão Preto, Brazil., Franca-Neto PL; Department of Genetics, Federal University of Pernambuco, Recife, Brazil., Quek L; Department of Hematology, Oxford University Hospitals National Health Service (NHS) Foundation Trust, Oxford, United Kingdom.; Medical Research Council (MRC) Molecular Hematology Unit, Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, United Kingdom., Corby A; Medical Research Council (MRC) Molecular Hematology Unit, Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, United Kingdom., Oliveira MM; Department of Genetics, Federal University of Pernambuco, Recife, Brazil., Lima MM; Department of Genetics, Federal University of Pernambuco, Recife, Brazil., de Assis RA; Department of Internal Medicine, Hematology and Hemotherapy Foundation of Pernambuco, Recife, Brazil., de Melo Campos P; Hematology and Transfusion Medicine Center and., Duarte BK; Hematology and Transfusion Medicine Center and.; Department of Internal Medicine, University of Campinas, Campinas, São Paulo, Brazil; and., Bendit I; Hematology Division, LIM31, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil., Rocha V; Hematology Division, LIM31, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil., Rego EM; Hematology Division, LIM31, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil., Traina F; Department of Internal Medicine, Medical School of Ribeirão Preto, Ribeirão Preto, Brazil., Saad ST; Hematology and Transfusion Medicine Center and.; Department of Internal Medicine, University of Campinas, Campinas, São Paulo, Brazil; and., Beltrão EI; Department of Biochemistry, Federal University of Pernambuco, Recife, Brazil., Bezerra MA; Department of Genetics, Federal University of Pernambuco, Recife, Brazil., Lucena-Araujo AR; Department of Genetics, Federal University of Pernambuco, Recife, Brazil.
Jazyk: angličtina
Zdroj: Blood [Blood] 2020 Mar 12; Vol. 135 (11), pp. 870-875.
DOI: 10.1182/blood.2019003339
Databáze: MEDLINE