Pathway dependent shape-transformation of azide-decorated polymersomes.

Autor:	Che H; Eindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB Eindhoven, The Netherlands. j.c.m.v.hest@tue.nl l.k.e.a.abdelmohsen@tue.nl., de Windt LNJ; Eindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB Eindhoven, The Netherlands. j.c.m.v.hest@tue.nl l.k.e.a.abdelmohsen@tue.nl., Zhu J; Eindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB Eindhoven, The Netherlands. j.c.m.v.hest@tue.nl l.k.e.a.abdelmohsen@tue.nl., Pijpers IAB; Eindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB Eindhoven, The Netherlands. j.c.m.v.hest@tue.nl l.k.e.a.abdelmohsen@tue.nl., Mason AF; Eindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB Eindhoven, The Netherlands. j.c.m.v.hest@tue.nl l.k.e.a.abdelmohsen@tue.nl., Abdelmohsen LKEA; Eindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB Eindhoven, The Netherlands. j.c.m.v.hest@tue.nl l.k.e.a.abdelmohsen@tue.nl., van Hest JCM; Eindhoven University of Technology, Institute for Complex Molecular Systems, P.O. Box 513 (STO 3.41), 5600MB Eindhoven, The Netherlands. j.c.m.v.hest@tue.nl l.k.e.a.abdelmohsen@tue.nl.
Jazyk:	angličtina
Zdroj:	Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Feb 18; Vol. 56 (14), pp. 2127-2130. Date of Electronic Publication: 2020 Jan 23.
DOI:	10.1039/c9cc08944f
Abstrakt:	Here we report the shape transformation of poly(ethylene glycol)-polystyrene (PEG-PS) polymersomes into ordered inverse morphologies, directed by the salt concentration of the medium and the presence of azide groups on the polymersome surface. The azide moieties introduced at the chain ends of the PEG blocks induce a difference in hydrodynamic volume of the hydrophilic domains at the inner and outer side of the vesicular membrane, allowing control over its spontaneous curvature and hence the pathway of shape deformation. This simple modification enables access to intricate morphologies which are traditionally only accessible via the application of complex polymer building blocks.
Databáze:	MEDLINE
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