A Review of the Scientific Rigor, Reproducibility, and Transparency Studies Conducted by the ABRF Research Groups.

Autor:	Mische SM; New York University (NYU) Langone Medical Center, New York, New York 10016, USA., Fisher NC; University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA., Meyn SM; Vanderbilt University Medical Center, Nashville, Tennessee 37212, USA., Sol-Church K; University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA., Hegstad-Davies RL; University of Minnesota, Minneapolis, Minnesota 55455, USA., Weis-Garcia F; Sloan Kettering Memorial Cancer Center, New York, New York 10065, USA., Adams M; Van Andel Institute, Grand Rapids, Michigan 49503, USA., Ashton JM; University of Rochester Medical Center, West Henrietta, New York 14642, USA., Delventhal KM; Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA., Dragon JA; University of Vermont, Burlington, Vermont 05405, USA., Holmes L; Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA., Jagtap P; University of Minnesota, Minneapolis, Minnesota 55455, USA., Kubow KE; James Madison University, Harrisonburg, VA 22807, USA., Mason CE; Weill Cornell School of Medicine, New York, New York 10065, USA., Palmblad M; Leiden University Medical Center, Leiden 2333, The Netherlands., Searle BC; Institute for Systems Biology, Seattle, Washington 98109, USA., Turck CW; Max Planck Institute of Psychiatry, Munich 80804, Germany; and., Knudtson KL; University of Iowa, Iowa City, Iowa 52242, USA.
Jazyk:	angličtina
Zdroj:	Journal of biomolecular techniques : JBT [J Biomol Tech] 2020 Apr; Vol. 31 (1), pp. 11-26.
DOI:	10.7171/jbt.20-3101-003
Abstrakt:	Shared research resource facilities, also known as core laboratories (Cores), are responsible for generating a significant and growing portion of the research data in academic biomedical research institutions. Cores represent a central repository for institutional knowledge management, with deep expertise in the strengths and limitations of technology and its applications. They inherently support transparency and scientific reproducibility by protecting against cognitive bias in research design and data analysis, and they have institutional responsibility for the conduct of research (research ethics, regulatory compliance, and financial accountability) performed in their Cores. The Association of Biomolecular Resource Facilities (ABRF) is a FASEB-member scientific society whose members are scientists and administrators that manage or support Cores. The ABRF Research Groups (RGs), representing expertise for an array of cutting-edge and established technology platforms, perform multicenter research studies to determine and communicate best practices and community-based standards. This review provides a summary of the contributions of the ABRF RGs to promote scientific rigor and reproducibility in Cores from the published literature, ABRF meetings, and ABRF RGs communications. (© Association of Biomolecular Resource Facilities.)
Databáze:	MEDLINE
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