Kinesiophobia contributes to pain-related disability in breast cancer survivors: a cross-sectional study.

Autor: Van der Gucht E; Department of Rehabilitation Sciences, KU Leuven, University of Leuven, ON4 Herestraat 49 - box 1510, 3000, Leuven, Belgium. elien.vandergucht@kuleuven.be.; Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium. elien.vandergucht@kuleuven.be., Dams L; Department of Rehabilitation Sciences, KU Leuven, University of Leuven, ON4 Herestraat 49 - box 1510, 3000, Leuven, Belgium.; Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium., Meeus M; Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium., Devoogdt N; Department of Rehabilitation Sciences, KU Leuven, University of Leuven, ON4 Herestraat 49 - box 1510, 3000, Leuven, Belgium.; Department of Vascular Surgery and Department of Physical Medicine and Rehabilitation, Center for Lymphoedema, UZ Leuven, University Hospitals Leuven, Leuven, Belgium., Beintema A; The Berekuyl Academy, Hierden, the Netherlands.; Cancer Care Center, Amsterdam, the Netherlands., Penen F; Department of Rehabilitation Sciences, KU Leuven, University of Leuven, ON4 Herestraat 49 - box 1510, 3000, Leuven, Belgium.; Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium., Hoelen W; The Berekuyl Academy, Hierden, the Netherlands., De Vrieze T; Department of Rehabilitation Sciences, KU Leuven, University of Leuven, ON4 Herestraat 49 - box 1510, 3000, Leuven, Belgium.; Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium., De Groef A; Department of Rehabilitation Sciences, KU Leuven, University of Leuven, ON4 Herestraat 49 - box 1510, 3000, Leuven, Belgium.; Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium.
Jazyk: angličtina
Zdroj: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer [Support Care Cancer] 2020 Sep; Vol. 28 (9), pp. 4501-4508. Date of Electronic Publication: 2020 Jan 17.
DOI: 10.1007/s00520-020-05304-4
Abstrakt: Purpose: Pain is one of the most prevalent problems reported by breast cancer survivors. As this long-lasting complication can result in disabilities on all different domains of functioning, we aimed to clarify the contribution of different factors (pain-related factors, psychosocial factors, and fatigue) to pain-related disability in female breast cancer survivors.
Methods: Seventy women who had completed their primary breast cancer treatment were included in this cross-sectional study. The following outcome measures were evaluated as independent variables for their contribution to pain-related disability (measured by the Pain Disability Index, with a maximum score of 70): pain intensity, self-reported symptoms of central sensitization, fatigue, illness beliefs, pain catastrophizing, and kinesiophobia. At first, bi- and multivariable regression methods were conducted. Secondly, a stepwise regression analysis was performed to determine the explained variance of the PDI.
Results: Mean score on the PDI was 16 at 4.5 years post-surgery. Multivariable regression analysis revealed higher levels of kinesiophobia as the main contributor to pain-related disability. Ultimately, stepwise regression showed that up to 40% of variance in pain-related disability could be explained by kinesiophobia, negative perceptions related to illness consequences, and pain catastrophizing.
Conclusion: This study shows that breast cancer survivors portray moderate self-reported pain-related disability. Kinesiophobia emerged as the main contributor to pain-related disability at this time point, which could shine a light on the improvement of treatment modalities for pain management in this population.
Databáze: MEDLINE
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