| Autor: |
Yap S, Cheong JKK, Ooi EH, Liao IY, Foo JJ, Nair SR, Mohd Ali AF |
| Jazyk: |
angličtina |
| Zdroj: |
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2019 Jul; Vol. 2019, pp. 2887-2890. |
| DOI: |
10.1109/EMBC.2019.8857816 |
| Abstrakt: |
The commonly used radiofrequency ablation (RFA) technique for treating liver cancer is in the monopolar mode. This requires the insertion of the RF electrode directly into the tumor tissue, which increases the risks of tumor track seeding (TTS). One way to overcome TTS is by employing the bipolar RFA, implemented in the no-touch mode. In the no-touch mode, two RF electrodes are inserted into the healthy tissue that surrounds the tumor. The distance between the electrodes and the tumor is defined as the no-touch gap. The ability of the no-touch bipolar RFA to overcome TTS has been demonstrated in laboratory studies; however, little is known about the thermo-physiological responses of the tissue during the ablation process of the no-touch procedure. This will be investigated numerically in the present study. A 3D model of the liver tissue is developed and the no-touch bipolar RFA implemented using a pair of RF electrodes is simulated using the finite element method. In particular, the effects of the no-touch gap on the treatment outcome of the RFA procedure are investigated. Results show that a larger no-touch gap may result incomplete tumor destruction due to the central region of the tumor not being directly affected by the Joule heating phenomenon that is more prominent around the electrodes. This suggests that an improperly selected no-touch gap may result in a reduced efficiency of the no-touch bipolar RFA. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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