The utility of EBUS-TBNA in the diagnosis of suspected intrathoracic recurrence after esophageal cancer surgery.

Autor:	Chi J; Department of Endoscopy, Sun Yat-Sen University Cancer Center Guangzhou, Guangdong, China.; State Key Laboratory of Oncology in South China, Sun Yat-sen University Guangzhou, Guangdong, China., Lian SS; Department of Radiology, Sun Yat-Sen University Cancer Center Guangzhou, Guangdong, China, and.; State Key Laboratory of Oncology in South China, Sun Yat-sen University Guangzhou, Guangdong, China., Yang Q; Department of Endoscopy, Sun Yat-Sen University Cancer Center Guangzhou, Guangdong, China.; State Key Laboratory of Oncology in South China, Sun Yat-sen University Guangzhou, Guangdong, China., Luo GY; Department of Endoscopy, Sun Yat-Sen University Cancer Center Guangzhou, Guangdong, China.; State Key Laboratory of Oncology in South China, Sun Yat-sen University Guangzhou, Guangdong, China., Xu GL; Department of Endoscopy, Sun Yat-Sen University Cancer Center Guangzhou, Guangdong, China.; State Key Laboratory of Oncology in South China, Sun Yat-sen University Guangzhou, Guangdong, China.
Jazyk:	angličtina
Zdroj:	Japanese journal of clinical oncology [Jpn J Clin Oncol] 2020 May 05; Vol. 50 (5), pp. 602-608.
DOI:	10.1093/jjco/hyz212
Abstrakt:	Objectives: Postoperative recurrences, especially anastomotic recurrence and regional lymph node recurrence were common in patients even with curative esophageal cancer surgery. Endobronchial ultrasound-guided transbronchial needle aspiration is an alternative to mediastinoscopy in patients with lung cancer and mediastinal lymphadenopathy. The aim of our study is to evaluate the utility of endobronchial ultrasound-guided transbronchial needle aspiration in postoperative patients suffered from esophageal malignancy. Methods: All endobronchial ultrasound-guided transbronchial needle aspiration cases performed between August 2015 and December 2018 in our center were all retrospective reviewed. The patients with enlarged mediastinal lymph node and/or unknown intrathoracic mass after esophageal cancer surgery were enrolled. Final diagnoses were determined by the result of endobronchial ultrasound-guided transbronchial needle aspiration, second surgery and/or clinical follow-up for at least 6 months. Results: Overall 29 patients were included in the analysis with 30 lesions sampled. No endobronchial ultrasound-guided transbronchial needle aspiration related complications were observed. In total, 22 of these (73.3%) had a diagnosis of tumor recurrence, whereas eight (26.7%) had a different diagnosis: two (6.7%) had a second primary malignancy and three (10.0%) had non-neoplastic diagnosis. Cases were false-negative in 3 (10.0%) out of 30 lesions. The overall sensitivity, negative predicted value and diagnostic accuracy were 88.9, 50.0 and 90.0%, respectively. Conclusions: Given its safety, low invasiveness, high sensitivity and diagnostic accuracy, endobronchial ultrasound-guided transbronchial needle aspiration could be considered for mediastinal lymphadenopathy and intrathoracic masses of unknown origin in patients after radical esophageal cancer resection, and its strategic role in the management of these patients was confirmed. (© The Author(s) 2020. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permission@oup.com.)
Databáze:	MEDLINE
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