Chronic Sheehan's Syndrome - A Differential to be Considered in Clinical Practice in Women with a History of Postpartum Hemorrhage.

Autor: Jose M; Internal Medicine, Saint Peters University Hospital, New Brunswick, USA., Amir S; Internal Medicine, Saint Peters University Hospital, New Brunswick, USA., Desai R; Internal Medicine, Saint Peters University Hospital, New Brunswick, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2019 Dec 04; Vol. 11 (12), pp. e6290. Date of Electronic Publication: 2019 Dec 04.
DOI: 10.7759/cureus.6290
Abstrakt: Sheehan's syndrome is hypopituitarism due to pituitary gland necrosis resulting from hemorrhagic shock during pregnancy. It is a rare complication with varied manifestations and a considerable delay in diagnosis. We describe the case of a 36-year-old female with eight years of non-specific symptoms of generalized myalgias and intense fatigue managed symptomatically all these years. Further clinical assessment revealed amenorrhea and agalactia ongoing for several years without a clinical diagnosis. A good history and physical led to the diagnosis during a routine outpatient visit. She had significant improvement noted following the commencement of treatment. Previous case reports describe cases being diagnosed after one or other complications from long-term panhypopituitarism. Through this case, we want to illustrate that undiagnosed Sheehan's syndrome is associated with long-term morbidity, and there should be a high index of suspicion for it to be diagnosed during a routine clinical visit and thus prevent complications before a diagnosis can be made. It is essential to create awareness, especially in developed countries like the United States, where it has received less attention over the last few years.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2019, Jose et al.)
Databáze: MEDLINE