[Anti-NMDAR encephalitis associated with relapsing optic neuritis: a case report and differential diagnosis].

Autor: Belova AN; FSBEI HE 'Privolzhsky Research Medical University', Nizhny Novgorod, Russia., Grygorieva VN; FSBEI HE 'Privolzhsky Research Medical University', Nizhny Novgorod, Russia., Rasteryaeva MV; FSBEI HE 'Privolzhsky Research Medical University', Nizhny Novgorod, Russia., Ruina EA; FSBEI HE 'Privolzhsky Research Medical University', Nizhny Novgorod, Russia., Belova EM; State Budgetary Healthcare Institute 'City Clinical Hospital #3', Nizhny Novgorod, Russia., Solovieva VS; State Budgetary Healthcare Institute 'City Clinical Hospital #3', Nizhny Novgorod, Russia., Boyko AN; Pirogov National Russian Scientific Medical University, Moscow, Russia; Federal Center of Cerebrovascular Pathology and Stroke, Moscow, Russia.
Jazyk: ruština
Zdroj: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2019; Vol. 119 (10. Vyp. 2), pp. 137-146.
DOI: 10.17116/jnevro2019119102137
Abstrakt: Autoimmune encephalitis with antibodies to NMDA receptors, or anti-NMDAR encephalitis, is the most common form of autoimmune encephalitis. The disease is curable, however, the lack of timely therapy can lead to the disability of patients or to the death. Difficulties in the diagnosis of anti-NMDAR encephalitis are caused by the heterogeneity of its manifestations, a possible overlapping with other autoimmune diseases and insufficient awareness about this form of encephalitis. This article presents the literature review and describes the case of anti-NMDAR encephalitis associated with recurrent optic neuritis, which might be an atypical manifestation for this disease. Optic neuritis could not be explained by overlapping with multiple sclerosis or neuromyelitis optica spectrum disorders.
Databáze: MEDLINE