Conventional and Emerging Markers in Stem Cell Isolation and Characterization.

Autor:	Kavyasudha C; Department of Genetic Engineering, SRM Institute of Science and Technology, Kattankulathur, Chennai, Tamil Nadu, India., Joseph JP; Department of Genetic Engineering, SRM Institute of Science and Technology, Kattankulathur, Chennai, Tamil Nadu, India., Jayaraj R; College of Health and Human Sciences, Charles Darwin University, Darwin, NT, Australia., Pillai AA; Department of Genetic Engineering, SRM Institute of Science and Technology, Kattankulathur, Chennai, Tamil Nadu, India., Devi A; Department of Genetic Engineering, SRM Institute of Science and Technology, Kattankulathur, Chennai, Tamil Nadu, India. adevipradeep@gmail.com.
Jazyk:	angličtina
Zdroj:	Advances in experimental medicine and biology [Adv Exp Med Biol] 2021; Vol. 1341, pp. 1-14.
DOI:	10.1007/5584_2019_475
Abstrakt:	Stem cells have emerged as a promising source of cell-based therapy in regenerative medicine with several stem cell-based products currently in clinical trials. Despite the immense therapeutic potential, their isolation from some of the emerging sources and their characterization has been naïve owing to the lack of standard markers for the same. Some biomarkers have now been well established for the isolation and characterization of stem cells. However, there are emerging markers that can be used in addition to these conventional markers or independent of them to establish the identity of the stem cells. In this review, an attempt has been made to describe a few conventionally used markers and emerging markers for the identification, isolation and characterization of stem cells from various niches across the three germ layer origins. (© 2019. Springer Nature Switzerland AG.)
Databáze:	MEDLINE
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