Dietary glycaemic index, glycaemic load and head and neck cancer risk: a pooled analysis in an international consortium.

Autor: Chang CP; Division of Public Health, Department of Family & Preventive Medicine, University of Utah School of Medicine, and Huntsman Cancer Institute, 375 Chipeta Way, Suite A, Salt Lake City, UT, 84108, USA., La Vecchia C; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, via Venezian, 1, 20133, Milano, Italy., Serraino D; Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, via Gallini, 2, 33081, Aviano, Italy., Olshan AF; Department of Epidemiology, Gillings School of Global Public Health, Campus Box 7435, Chapel Hill, NC, 27599, USA., Zevallos JP; Division of Head and Neck Surgical Oncology, Department of Otolaryngology/Head and Neck Surgery, Washington University School of Medicine, 660 S. Euclid Ave., Campus Box 8115, St. Louis, MO, 63110, USA., Morgenstern H; Departments of Epidemiology and Environmental Health Sciences, School of Public Health, and Department of Urology, Medical School, University of Michigan, 1415 Washington Heights, M5164 SPH-II, Ann Arbor, MI, 48109-2029, USA., Levi F; Institut Universitaire de Médecine Sociale et Préventive (IUMSP), Unisanté, University of Lausanne, Route de la Corniche 10, 1010, Lausanne, Switzerland., Garavello W; Department of Otorhinolaryngology, School of Medicine and Surgery, University of Milano-Bicocca, via Pergolesi, 33, 20052, Monza, Italy., Kelsey K; Department of Epidemiology and Department of Laboratory Medicine and Pathology, Brown University, 70 Ship Street, Providence, RI, 02912, USA., McClean M; Boston University School of Public Health, 715 Albany St Talbot Building, Boston, MA, 02118, USA., Chen C; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA, 98109, USA., Schwartz SM; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA, 98109, USA., Schantz S; New York Eye and Ear Infirmary, 310 East 14th Street, New York, NY, 10003, USA., Yu GP; Department of Otolaryngology, School of Medicine, New York Medical College, Valhalla, New York, NY, USA., Boffetta P; The Tisch Cancer Institute, Mount Sinai School of Medicine, 17 E 102 St 4th Floor Room 4-110, New York, NY, 10029, USA.; Department of Medical and Surgical Sciences, University of Bologna, via Massarenti, 9, 40138, Bologna, Italy., Hashibe M; Division of Public Health, Department of Family & Preventive Medicine, University of Utah School of Medicine, and Huntsman Cancer Institute, 375 Chipeta Way, Suite A, Salt Lake City, UT, 84108, USA., Lee YA; Division of Public Health, Department of Family & Preventive Medicine, University of Utah School of Medicine, and Huntsman Cancer Institute, 375 Chipeta Way, Suite A, Salt Lake City, UT, 84108, USA., Parpinel M; Department of Medicine, University of Udine, via Colugna, 50, 33100, Udine, Italy., Augustin LSA; Epidemiology and Biostatistics Unit, Istituto Nazionale Tumori IRCCS 'Fondazione G. Pascale', via Semmola, 53, 80131, Napoli, Italy.; Clinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital, 61, Queen St. East, Toronto, ON, M5C 2T2, Canada., Turati F; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, via Venezian, 1, 20133, Milano, Italy., Zhang ZF; Department of Epidemiology, UCLA Fielding School of Public Health, 71-225 CHS, Box 951772, Los Angeles, CA, 90095, USA., Edefonti V; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, via Venezian, 1, 20133, Milano, Italy. valeria.edefonti@unimi.it.
Jazyk: angličtina
Zdroj: British journal of cancer [Br J Cancer] 2020 Mar; Vol. 122 (6), pp. 745-748. Date of Electronic Publication: 2020 Jan 13.
DOI: 10.1038/s41416-019-0702-4
Abstrakt: High dietary glycaemic index (GI) and glycaemic load (GL) may increase cancer risk. However, limited information was available on GI and/or GL and head and neck cancer (HNC) risk. We conducted a pooled analysis on 8 case-control studies (4081 HNC cases; 7407 controls) from the International Head and Neck Cancer Epidemiology (INHANCE) consortium. We estimated the odds ratios (ORs) and 95% confidence intervals (CIs) of HNC, and its subsites, from fixed- or mixed-effects logistic models including centre-specific quartiles of GI or GL. GI, but not GL, had a weak positive association with HNC (OR Q4 vs. Q1  = 1.16; 95% CI = 1.02-1.31). In subsites, we found a positive association between GI and laryngeal cancer (OR Q4 vs. Q1  = 1.60; 95% CI = 1.30-1.96) and an inverse association between GL and oropharyngeal cancer (OR Q4 vs. Q1  = 0.78; 95% CI = 0.63-0.97). This pooled analysis indicates a modest positive association between GI and HNC, mainly driven by laryngeal cancer.
Databáze: MEDLINE