The study of seroprevalence of hepatitis E virus and an investigation into the lifestyle behaviours of the aborigines in Malaysia.
Autor: | Wong LP; Centre for Epidemiology and Evidence-Based Practice, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Alias H; Centre for Epidemiology and Evidence-Based Practice, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Choy SH; Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Goh XT; Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Lee SC; Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Lim YAL; Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Kee BP; Department of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Chua KH; Department of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Kamaruzaman A; Dean's Office, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Zheng Z; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University, Xiamen, China., Zhao Q; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University, Xiamen, China., Wu T; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University, Xiamen, China. |
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Jazyk: | angličtina |
Zdroj: | Zoonoses and public health [Zoonoses Public Health] 2020 May; Vol. 67 (3), pp. 263-270. Date of Electronic Publication: 2020 Jan 12. |
DOI: | 10.1111/zph.12681 |
Abstrakt: | Malaysia is a non-endemic country for hepatitis E virus (HEV) infection. However, seroprevalence as high as 50% among samples of aboriginal people were reported over two decades ago. A total of 207 samples collected from seven aboriginal villages in rural settlements across two states in Malaysia were analysed for anti-HEV IgG and IgM by an enzyme-linked immunoassay. Following the detection of anti-HEV seroprevalence, we organized health outreach to inform and educate the community. Qualitative interviews were conducted with individuals tested positive for anti-HEV antibodies. Data derived from interviews and observations were used to investigate possible lifestyle behaviours associated with HEV infection. Anti-HEV IgG was detected in six samples (5.9%) from the village of Dusun Kubur. Qualitative inquiry and observation study revealed poor dietary and household hygiene, contaminated food and water, contact with animal faeces, unsanitary and domestic waste disposal, and wildlife reservoirs could be the contributing factors for transmission and acquisition of HEV infection. Investigation during health outreach is important to provide insights for future empirical research and implementation for improvement of lifestyle behaviours among the aborigines. Managing the risk of HEV infection in the aborigines may reduce the risk of HEV transmission to the local communities. (© 2020 Blackwell Verlag GmbH.) |
Databáze: | MEDLINE |
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