The plateau at V˙ O 2max is associated with anaerobic alleles.

Autor: Keiller DR; Faculty of Science and Engineering, School of Life Sciences, Anglia Ruskin University, UK. Electronic address: don.keiller@anglia.ac.uk., Gordon DA; Faculty of Science and Engineering, School Psychology and Sports Science, Anglia Ruskin University, UK.
Jazyk: angličtina
Zdroj: Journal of science and medicine in sport [J Sci Med Sport] 2020 May; Vol. 23 (5), pp. 506-511. Date of Electronic Publication: 2019 Dec 12.
DOI: 10.1016/j.jsams.2019.11.012
Abstrakt: Objectives: This study tests the hypothesis that individuals who achieve a plateau at V˙ O 2max (V˙ O 2plat ) are more likely to possess alleles, associated with anaerobic capacity, than those who do not.
Design: A literature survey, physiological testing and genetic analysis was used to determine any association between the aerobic and anaerobic polymorphisms of 40 genes and V˙ O 2plat .
Methods: 34, healthy, Caucasian volunteers, completed an exercise test to determine V˙ O 2max, and  V˙ O 2plat . 28 of the volunteers agreed to DNA testing and 26 were successfully genotyped. A literature search was used to determine whether the 40 polymorphisms analysed were associated with aerobic, or anaerobic exercise performance.
Results: The literature survey enabled classification of the 40 target alleles as aerobic [11], anaerobic [24], or having no apparent association (NAA) [5] with exercise performance. It also found no previous studies linking a genetic component with the ability to achieve V˙ O 2plat . Independent t-tests showed a significant difference (p < 0.001) in the ability to achieve V˙ O 2plat , but no other measured physiological variable was significantly different. Pearson's χ 2 testing demonstrated a highly significant association (p = 0.008) between anaerobic allele frequency and V˙ O 2plat , but not with V˙ O 2max . There was no association between aerobic alleles and V˙ O 2plat , or V˙ O 2max . Finally there were no significant differences in the allelic frequencies, observed in this study and those expected of Northern and Western European Caucasians.
Conclusion: These results support the hypothesis that the ability to achieve V˙ O 2plat is associated with alleles linked to anaerobic exercise capacity.
(Copyright © 2019 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: