| Autor: |
Kalsin AM; A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov str., 119991 Moscow, Russia., Peganova TA; A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov str., 119991 Moscow, Russia., Sinopalnikova IS; A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov str., 119991 Moscow, Russia and CNRS, Laboratoire de Chimie de Coordination, Université de Toulouse, UPS, INPT, 205 Route de Narbonne, 31077 Toulouse Cedex 4, France. rinaldo.poli@lcc-toulouse.fr., Fedyanin IV; A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov str., 119991 Moscow, Russia., Belkova NV; A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov str., 119991 Moscow, Russia., Deydier E; CNRS, Laboratoire de Chimie de Coordination, Université de Toulouse, UPS, INPT, 205 Route de Narbonne, 31077 Toulouse Cedex 4, France. rinaldo.poli@lcc-toulouse.fr., Poli R; CNRS, Laboratoire de Chimie de Coordination, Université de Toulouse, UPS, INPT, 205 Route de Narbonne, 31077 Toulouse Cedex 4, France. rinaldo.poli@lcc-toulouse.fr and Institut Universitaire de France, 1, rue Descartes, 75231 Paris Cedex 05, France. |
| Abstrakt: |
A series of arene ruthenium iminophosphonamide complexes, [(Arene)RuCl{R 2 P(NR') 2 }] (1), bearing various arenes and R,R' substituents on the NPN ligand have been investigated as precatalysts in acetophenone transfer hydrogenation in basic and base-free isopropanol. The results clearly demonstrate the presence of two distinct reaction mechanisms, which are controlled by the basicity of the N-atoms. Complexes 1 in which both R' substituents are aryl groups are only active once the neutral hydride complex [(Arene)RuH{R 2 P(NR') 2 }] (2) is generated in basic isopropanol, the latter being able to reduce a ketone via a stepwise hydride and proton transfer. On the other hand, complexes in which at least one R' group is Me readily catalyze the reaction in the absence of base. In the latter case, the results of kinetic studies and DFT calculations support an outer-sphere concerted asynchronous hydride and proton transfer assisted by the basic N-atom of the NPN ligand, which promotes catalysis via precoordination of an alcohol molecule by hydrogen bonding. |
