Association of monocyte to high-density lipoprotein ratio with bare-metal stent restenosis in STEMI patients treated with primary PCI.

Autor:	Avci II; Department of Cardiology, University of Health Sciences, Dr. Siyami Ersek Training and Research Hospital, Istanbul, Turkey., Sahin I; Department of Cardiology, University of Health Sciences, Bağcılar Training and Research Hospital, Istanbul, Turkey., Gungor B; Department of Cardiology, University of Health Sciences, Dr. Siyami Ersek Training and Research Hospital, Istanbul, Turkey., Karatas MB; Department of Cardiology, University of Health Sciences, Dr. Siyami Ersek Training and Research Hospital, Istanbul, Turkey., Ozcan KS; Department of Cardiology, Derince Training and Research Hospital, Kocaeli, Turkey., Canga Y; Department of Cardiology, University of Health Sciences, Dr. Siyami Ersek Training and Research Hospital, Istanbul, Turkey., Keskin M; Department of Cardiology, University of Health Sciences, Dr. Siyami Ersek Training and Research Hospital, Istanbul, Turkey., Hayiroglu MI; Department of Cardiology, University of Health Sciences, Dr. Siyami Ersek Training and Research Hospital, Istanbul, Turkey., Karadeniz FO; Department of Cardiology, Erzurum Training and Research Hospital, Erzurum, Turkey., Sungur A; Department of Cardiology, Kahramanmaras Necip Fazil State Hospital, Kahramanmaras, Turkey.
Jazyk:	angličtina
Zdroj:	Northern clinics of Istanbul [North Clin Istanb] 2018 Dec 21; Vol. 6 (4), pp. 393-400. Date of Electronic Publication: 2018 Dec 21 (Print Publication: 2019).
DOI:	10.14744/nci.2018.93653
Abstrakt:	Objective: Monocyte to high-density lipoprotein ratio (MHR) has recently been postulated as a novel parameter related to adverse cardiovascular outcomes. In this study, we aimed to investigate the correlation of MHR with stent restenosis (SR) rates after the primary percutaneous coronary intervention (PCI) and bare-metal stent (BMS) implantation. Methods: In this study, patients who had undergone primary PCI for STEMI and had a control angiogram during follow-up were retrospectively recruited. Patients were categorized according to admission MHR tertiles, clinical and angiographic data were compared. In addition, predictors of SR were evaluated with logistic regression analysis. Results: A total number of 448 patients (240 patients with SR and 208 patients without SR) were included in this study. Patients were categorized into three groups according to tertiles of admission MHR. During a follow-up period of median 12 months, the rate of SR was significantly higher in patients with higher MHR levels (45% in tertile 1, 54% in tertile 2 and 62% in tertile 3, p<0.01). In multivariate Cox regression analysis, male gender, stent length, admission NLR levels and MHR levels (HR 1.03, 95% CI 1.02-1.06, p<0.01) remained as the independent predictors of SR in the study population. Conclusion: Gender, stent length, higher MHR and NLR levels are correlated to SR after primary PCI. Competing Interests: Conflict of Interest: The authors have nothing to declare. (Copyright: © 2019 by Istanbul Northern Anatolian Association of Public Hospitals.)
Databáze:	MEDLINE
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