| Autor: |
Muro BBD; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Carnevale RF; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Leal DF; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Torres MA; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Mendonça MV; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Nakasone DH; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Martinez CHG; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Ravagnani GM; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Monteiro MS; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Poor AP; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Martins SMMK; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Viau P; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Oliveira CA; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil., Pulz LH; Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Pirassununga13635-900, Brazil., Strefezzi RF; Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Pirassununga13635-900, Brazil., Almond GW; Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC27606, USA., de Andrade AFC; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo05508-270, Brazil. |
| Abstrakt: |
Progesterone (P4) plays a key role in pregnancy establishment and maintenance; during early pregnancy, P4 stimulates the production and release of uterine secretions necessary for conceptus growth prior to implantation; therefore, exogenous P4 supplementation may improve embryo development. This study evaluated the effects of supplementation during early pregnancy with long-acting injectable progesterone or altrenogest on embryonic characteristics of sows and gilts. Thus, a total of 32 sows and 16 gilts were used. On day 6 of pregnancy sows and gilts were allocated to one of the following groups: non-supplemented; supplemented with 20 mg of altrenogest, orally, from days 6 to 12 of pregnancy; supplemented with 2.15 mg/kg of long-acting injectable progesterone on day 6 of pregnancy. Animals were killed on day 28 of pregnancy, and ovulation rate, embryo survival, embryo weight, crown-to-rump length, uterine glandular epithelium and endometrial vascularization were assessed. Treatments had no effect on pregnancy rate, embryo survival or endometrial vascular density (P > 0.05). Non-supplemented gilts presented larger and heavier embryos compared to gilts from supplemented groups (P < 0.05). Sows in the altrenogest group presented larger and heavier embryos compared to non-supplemented sows and sows supplemented with long-acting injectable progesterone. In conclusion, supplementation of sows and gilts with progestagen from day 6 of pregnancy can be used as a means to improve embryo survival without deleterious effects. |
