| Autor: |
Mathur S, Koistinen GV, Horger EO 3rd, Mahvi TA, Fudenberg HH |
| Jazyk: |
angličtina |
| Zdroj: |
Infection and immunity [Infect Immun] 1977 Jan; Vol. 15 (1), pp. 287-94. |
| DOI: |
10.1128/iai.15.1.287-294.1977 |
| Abstrakt: |
Serum antibody titers to Candida albicans were estimated in 37 women with recurrent vaginal candidiasis and in 148 normal American and Finnish subjects, using the passive-hemagglutination technique. The antibody titers ranged from 0 to 16 in normal individuals and 4 to 256 in vaginal candidiasis patients. Antibodies to C. albicans in the sera of vaginal candidiasis patients were found to be the secretory immunoglobulin A type, as determined by gel filtration and double-diffusion tests. The results were confirmed by the indir-ct fluorescent-antibody technique. Our findings suggest that, in vaginal candidiasis, the antibody response is mainly local, consisting of secretory immunoglobulin A, some of which finds its way into systemic circulation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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