Comparison of Transforaminal Triamcinolone and Dexmedetomidine in Radicular Low-Back Pain: A Randomized Double-Blind Clinical Trial.

Autor:	Imani F; Pain Research Center, Iran University of Medical Sciences, Tehran, Iran., Rahimzadeh P; Pain Research Center, Iran University of Medical Sciences, Tehran, Iran., Khademi SH; Department of Anesthesiology, Mashhad University of Medical Sciences, Mashhad, Iran., Narimani Zamanabadi M; Department of Anesthesiology, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran., Sadegi K; Department of Anesthesiology, Zabol University of Medical Sciences, Zabol, Iran., Abolfazli-Karizi A; Pain Research Center, Iran University of Medical Sciences, Tehran, Iran.
Jazyk:	angličtina
Zdroj:	Anesthesiology and pain medicine [Anesth Pain Med] 2019 Oct 23; Vol. 9 (5), pp. e96117. Date of Electronic Publication: 2019 Oct 23 (Print Publication: 2019).
DOI:	10.5812/aapm.96117
Abstrakt:	Background: Administration of steroids in the lumbar transforaminal block for lumbar radicular pain is considered one of the preferred treatment methods though it is associated with some complications. Objectives: The effects and side effects of triamcinolone and dexmedetomidine in the lumbar transforaminal block were investigated in the present study. Methods: In this study, 30 patients, aged 40 - 70 years, suffering from lumbar radicular pain arising from the lumbar disc protrusion were equally divided into two groups of triamcinolone (T) and dexmedetomidine (D). They all underwent lumbar transforaminal blocks. An injection solution of triamcinolone (20 mg) plus ropivacaine (0.2%) and another one containing dexmedetomidine (50 μg) plus ropivacaine (0.2%) were administered in the triamcinolone and dexmedetomidine groups, respectively. Visual Analog Scale (VAS), Oswestry Disability Index (ODI), Straight Leg Raise (SLR or lasègue's test), and Fasting Blood Sugar (FBS) were measured at 0, 2 weeks, 1, 3, and 6 months post-procedure. The levels of calcium, magnesium, and vitamin D, as well as potential complications, were also evaluated. Results: Significant differences were found in the VAS and ODI during the measurement times within each group. The VAS and ODI were remarkably different between the dexmedetomidine group and the triamcinolone group. In addition, there were considerable differences in the increased FBS and reduced calcium and vitamin D levels in the triamcinolone group from changes in the dexmedetomidine group. Conclusions: The lumbar transforaminal block with triamcinolone or dexmedetomidine attenuates the lumbar radicular pain. Further, dexmedetomidine exerts a more potent pain relief effect than triamcinolone. Competing Interests: Conflict of Interests: No conflicts of interest are reported. (Copyright © 2019, Author(s).)
Databáze:	MEDLINE
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