Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018.

Autor:	Lee EJ; ICES, ON, Canada., Patel A; ICES, ON, Canada., Acedillo RR; Division of Nephrology, Department of Medicine, London Health Sciences Centre, ON, Canada.; Department of Epidemiology and Biostatistics, Western University, London, ON, Canada., Bachynski JC; Halton Healthcare Services, Oakville, ON, Canada., Barrett I; St. Michael's Hospital, Toronto, ON, Canada., Basile E; Office of Human Research Ethics, Western University, London, ON, Canada., Battistella M; Department of Pharmacy, University Health Network, Toronto, ON, Canada.; Leslie Dan Faculty of Pharmacy, University of Toronto, ON, Canada., Benjamin D; Royal Victoria Regional Health Centre, Barrie, ON, Canada., Berry D; Algoma Regional Renal Program, Sault Area Hospital, Sault Ste. Marie, ON, Canada., Blake PG; Division of Nephrology, Department of Medicine, London Health Sciences Centre, ON, Canada.; Ontario Renal Network, Cancer Care Ontario, Toronto, Canada., Chan P; Division of Nephrology, Department of Medicine, Michael Garron Hospital, Toronto, ON, Canada., Bohm CJ; Department of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada., Clemens KK; ICES, ON, Canada.; Department of Epidemiology and Biostatistics, Western University, London, ON, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, Western University, London, ON, Canada.; St. Joseph's Health Care London, ON, Canada., Cook C; Transplant Ambassador Program, Grand River Hospital, Kitchener, ON, Canada., Dember L; Renal, Electrolyte and Hypertension Division, Perelman School of Medicine, Philadelphia, PA, USA., Dirk JS; ICES, ON, Canada., Dixon S; ICES, ON, Canada.; Department of Epidemiology and Biostatistics, Western University, London, ON, Canada., Fowler E; The Kidney Foundation of Canada, Montreal, QC, Canada., Getchell L; Can-SOLVE CKD Network, Vancouver, BC, Canada., Gholami N; St. Joseph's Health Centre, Toronto, ON, Canada., Goldstein C; Rotman Institute of Philosophy, Western University, London, ON, Canada., Hahn E; ICES, ON, Canada., Hogeterp B; Lakeridge Health Oshawa, ON, Canada., Huang S; Division of Nephrology, Department of Medicine, London Health Sciences Centre, ON, Canada., Hughes M; Orillia Soldiers' Memorial Hospital, ON, Canada., Jardine MJ; Innovation & Kidney Research, The George Institute for Global Health, UNSW Sydney, Newtown, NSW, Australia., Kalatharan S; Can-SOLVE CKD Network, Vancouver, BC, Canada., Kilburn S; ICES, ON, Canada., Lacson E Jr; Tufts Medical Center, Boston, MA, USA., Leonard S; ICES, ON, Canada., Liberty C; The Ottawa Hospital, ON, Canada., Lindsay C; Scarborough Health Network, Toronto, ON, Canada., MacRae JM; Division of Nephrology, Department of Medicine, University of Calgary, AB, Canada., Manns BJ; Department of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada., McCallum J; Ontario Renal Network, Cancer Care Ontario, Toronto, Canada.; Renal Services, London Health Sciences Centre, ON, Canada., McIntyre CW; Kidney Clinical Research Unit, Lawson Health Research Institute, London, ON, Canada.; Department of Medical Biophysics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Molnar AO; ICES, ON, Canada.; Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada., Mustafa RA; Division of Nephrology and Hypertension, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, USA., Nesrallah GE; Division of Nephrology, Department of Medicine, Humber River Hospital, Toronto, ON, Canada., Oliver MJ; Division of Nephrology, Department of Medicine, University of Toronto, ON, Canada., Pandes M; Mackenzie Health, Richmond Hill, ON, Canada., Pandeya S; Halton Healthcare, Oakville, ON, Canada., Parmar MS; Kidney Care Centre, Timmins and District Hospital, ON, Canada., Rabin EZ; Niagara Health System, St. Catharines, ON, Canada., Riley J; Ontario SPOR SUPPORT Unit, Toronto, ON, Canada., Silver SA; Division of Nephrology, Kingston Health Sciences Center, Queen's University, Kingston, ON, Canada., Sontrop JM; ICES, ON, Canada.; Division of Nephrology, Department of Medicine, London Health Sciences Centre, ON, Canada.; Kidney Clinical Research Unit, Lawson Health Research Institute, London, ON, Canada., Sood MM; ICES, ON, Canada.; Division of Nephrology, Department of Medicine, University of Ottawa, ON, Canada., Suri RS; Division of Nephrology, Department of Medicine, McGill University, Montreal, QC, Canada.; Canadian Nephrology Trials Network, Canada., Tangri N; Chronic Disease Innovation Centre, Winnipeg, MB, Canada.; Department of Internal Medicine, University of Manitoba, Winnipeg, Canada., Tascona DJ; Ontario Renal Network, Cancer Care Ontario, Toronto, Canada.; Orillia Soldiers' Memorial Hospital, ON, Canada., Thomas A; St. Michael's Hospital, Toronto, ON, Canada., Wald R; St. Michael's Hospital, Toronto, ON, Canada.; Division of Nephrology, Department of Medicine, University of Toronto, ON, Canada., Walsh M; Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada.; Population Health Research Institute, Hamilton, ON, Canada., Weijer C; Department of Epidemiology and Biostatistics, Western University, London, ON, Canada.; Rotman Institute of Philosophy, Western University, London, ON, Canada., Weir MA; ICES, ON, Canada.; Division of Nephrology, Department of Medicine, London Health Sciences Centre, ON, Canada.; Kidney Clinical Research Unit, Lawson Health Research Institute, London, ON, Canada., Vorster H; Ontario Renal Network, Cancer Care Ontario, Toronto, Canada., Zimmerman D; Division of Nephrology, Department of Medicine, University of Ottawa, ON, Canada., Garg AX; ICES, ON, Canada.; Division of Nephrology, Department of Medicine, London Health Sciences Centre, ON, Canada.; Department of Epidemiology and Biostatistics, Western University, London, ON, Canada.; Kidney Clinical Research Unit, Lawson Health Research Institute, London, ON, Canada.
Jazyk:	angličtina
Zdroj:	Canadian journal of kidney health and disease [Can J Kidney Health Dis] 2019 Dec 26; Vol. 6, pp. 2054358119894394. Date of Electronic Publication: 2019 Dec 26 (Print Publication: 2019).
DOI:	10.1177/2054358119894394
Abstrakt:	Hemodialysis is a life-sustaining treatment for persons with kidney failure. However, those on hemodialysis still face a poor quality of life and a short life expectancy. High-quality research evidence from large randomized controlled trials is needed to identify interventions that improve the experiences, outcomes, and health care of persons receiving hemodialysis. With the support of the Canadian Institutes of Health Research and its Strategy for Patient-Oriented Research, the Innovative Clinical Trials in Hemodialysis Centers initiative brought together Canadian and international kidney researchers, patients, health care providers, and health administrators to participate in a workshop held in Toronto, Canada, on June 2 and 3, 2018. The workshop served to increase knowledge and awareness about the conduct of innovative, pragmatic, cluster-randomized registry trials embedded into routine hemodialysis care and provided an opportunity to discuss and build support for new trial ideas. The workshop content included structured presentations, facilitated group discussions, and expert panel feedback. Partnerships and promising trial ideas borne out of the workshop will continue to be developed to support the implementation of future large-scale trials. Competing Interests: Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. (© The Author(s) 2019.)
Databáze:	MEDLINE
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