The Effect of Body Composition and Energy Expenditure on Permethrin Biomarker Concentrations Among US Army National Guard Members.

Autor:	Scarpaci MM; United States Army Research Institute of Environmental Medicine, Military Performance Division, Natick (Mr Scarpaci, Ms Haven, Dr Maule, Dr Heaton, Dr Taylor, Dr Proctor); Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda (Mr Scarpaci, Dr Maule); Hassenfeld Child Health Innovation Institute, Brown University, Rhode Island (current affiliation) (Mr Scarpaci); Defense Health Agency - U.S. Army Satellite, Aberdeen Proving Ground, Maryland (current affiliation) (Dr Maule); Louisiana State University's Pennington Biomedical Research Center, Baton Rouge, Louisiana (Dr Rood); Division of Laboratory Sciences, Centers for Disease Control and Prevention, National Center for Environmental Health, Atlanta, Georgia (Dr Ospina, Dr Calafat); VA Boston Healthcare System, Research Service, Boston (Dr Proctor), Massachusetts., Haven CC, Maule AL, Heaton KJ, Taylor KM, Rood J, Ospina M, Calafat AM, Proctor SP
Jazyk:	angličtina
Zdroj:	Journal of occupational and environmental medicine [J Occup Environ Med] 2020 Mar; Vol. 62 (3), pp. 210-216.
DOI:	10.1097/JOM.0000000000001801
Abstrakt:	Objective: To examine relationships between percent body fat (%BF) and total energy expenditure (TEE) on permethrin exposure among Army National Guard (ARNG) Soldiers wearing permethrin-treated uniforms. Methods: ARNG members (n = 47) participated in a 9-day study. Repeated body composition (height, weight, %BF) measurements and daily urine samples, analyzed for permethrin and N,N-diethyl-meta-toluamide (DEET) metabolites, were collected. TEE was determined via doubly labeled water protocol. Linear mixed and regression models were used for analyses. Results: Neither %BF nor TEE were significantly associated with permethrin or DEET biomarkers. However, a significant interaction effect (F = 10.76; P = 0.0027) between laundering history and %BF was observed; 10% higher %BF was significantly associated with 25% higher permethrin biomarker concentrations among those wearing uniforms washed less than or equal to 25 (compared with more than 25) times. Conclusions: Uniform laundering history significantly affects the association between %BF and permethrin-treated uniform exposure.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu