| Autor: |
Kostyunin AE; Research Institute for Complex Issues of Cardiovascular Diseases., Ovcharenko EA; Research Institute for Complex Issues of Cardiovascular Diseases., Barbarash OL; Research Institute for Complex Issues of Cardiovascular Diseases. |
| Jazyk: |
ruština |
| Zdroj: |
Kardiologiia [Kardiologiia] 2019 Sep 12; Vol. 59 (11S), pp. 4-17. Date of Electronic Publication: 2019 Sep 12. |
| DOI: |
10.18087/cardio.n328 |
| Abstrakt: |
Calcific aortic valve stenosis (CAVS) is a serious socio-economic problem in developed countries because this disease is the most common indication for aortic valve replacement. Currently, there are no methods for non-invasive treatment of CAVS. Nevertheless, it is assumed that effective drug therapy for CAVS can be developed on the basis of modulators of the renin-angiotensin-aldosterone system (RAAS), which is involved in the pathogenesis of this disease. The purpose of this paper is to compile and analyze current information on the role of RAAS in the CAVS pathophysiology. Recent data on the effectiveness of RAAS inhibition are reviewed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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