Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective.

Autor: Qamar Z; Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi - 110062, India., Qizilbash FF; Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi - 110062, India., Iqubal MK; Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi - 110062, India., Ali A; Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi - 110062, India., Narang JK; Department of Pharmaceutics, Khalsa College of Pharmacy, Amritsar, Punjab-143001, India., Ali J; Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi - 110062, India., Baboota S; Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi - 110062, India.
Jazyk: angličtina
Zdroj: Recent patents on drug delivery & formulation [Recent Pat Drug Deliv Formul] 2019; Vol. 13 (4), pp. 246-254.
DOI: 10.2174/1872211314666191224115211
Abstrakt: The structure of the eye is very complex in nature which makes it a challenging task for pharmaceutical researchers to deliver the drug at the desired sites via different routes of administration. The development of the nano-based system helped in delivering the drug in the desired concentration. Improvement in penetration property, bioavailability, and residence time has all been achieved by encapsulating drugs into liposomes, dendrimers, solid lipid nanoparticle, nanostructured lipid carrier, nanoemulsion, and nanosuspension. This review puts emphasis on the need for nanomedicine for ocular drug delivery and recent developments in the field of nanomedicine along with recent patents published in the past few years.
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Databáze: MEDLINE
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