Prominin-1 and Photoreceptor Cadherin Localization in Xenopus laevis: Protein-Protein Relationships and Function.
| Autor: | Carr BJ; Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada. bjcarr@mail.ubc.ca., Yang LL; Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada., Moritz OL; Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada. |
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| Jazyk: | angličtina |
| Zdroj: | Advances in experimental medicine and biology [Adv Exp Med Biol] 2019; Vol. 1185, pp. 483-487. |
| DOI: | 10.1007/978-3-030-27378-1_79 |
| Abstrakt: | Retinal degenerative diseases are genetically diverse and rare inherited disorders that cause the death of rod and cone photoreceptors, resulting in progressive vision loss and blindness. This review will focus on two retinal degeneration-causing genes: prominin-1 (prom1) and photoreceptor cadherin (prCAD). We will discuss protein localization, potential roles in photoreceptor outer segment disc morphogenesis, and areas for future investigation. |
| Databáze: | MEDLINE |
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