Neurodevelopment of Nonmicrocephalic Children, After 18 Months of Life, Exposed Prenatally to Zika Virus.

Autor: Gerzson LR; Graduate Program in Child and Adolescent Health, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., de Almeida CS; Department of Physiotherapy, Physical Education and Dance, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Silva JHD; Graduate Program in Genetics and Molecular Biology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Feitosa MMA; Federal University of Amazonas, Manaus, Brazil., de Oliveira LN; Graduate Program in Science of Information, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Schuler-Faccini L; SIAT, Information Service on Teratogenic Agents, Medical Genetics Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Jazyk: angličtina
Zdroj: Journal of child neurology [J Child Neurol] 2020 Mar; Vol. 35 (4), pp. 278-282. Date of Electronic Publication: 2019 Dec 26.
DOI: 10.1177/0883073819892128
Abstrakt: The aim of this work was to evaluate the cognitive, language, and motor development, after 18 months of life, of nonmicrocephalic children born to mothers with Zika virus infection during pregnancy. Participants were 37 children aged 18-29 months divided into 2 groups: 17 nonmicrocephalic children born to mothers who had Zika virus infection during pregnancy (ZIKVG) and 20 nonmicrocephalic children with no maternal history of infection matched by sex and age (control group). A semistructured interview and the Bayley Scale of Infant and Toddler Development (Bayley III) were used for their evaluation. One child in the ZIKVG presented low cognitive score, the same in the control group. There were no statistical differences between the 2 groups regarding cognitive, language, and motor development. This sample, although small, showed that a significant proportion of nonmicrocephalic children exposed prenatally to Zika virus had normal development. A longer follow-up is necessary to observe if no other adverse outcomes will appear in the future.
Databáze: MEDLINE