Humidity-Insensitive Tissue Oxygen Tension Sensing for Wearable Devices † .

Autor: Roussakis E; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Cascales JP; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Marks HL; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Li X; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Grinstaff M; Departments of Biomedical Engineering and Chemistry, Boston University, Boston, MA., Evans CL; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Jazyk: angličtina
Zdroj: Photochemistry and photobiology [Photochem Photobiol] 2020 Mar; Vol. 96 (2), pp. 373-379. Date of Electronic Publication: 2020 Feb 12.
DOI: 10.1111/php.13198
Abstrakt: Quantification of tissue oxygen partial pressure (pO 2 ) at the skin surface is crucial for diagnostic applications in burns, reconstructive surgeries, diabetic ulcers, etc. Further, current advances in wearable and communications technologies have widened the use of transcutaneous oxygen monitors (TCOM) for home care or even enhance athletic performance. For TCOM technology to find widespread use, devices must function reliably yet independently of changes in environmental conditions, humidity in particular. To this end, we have explored the incorporation of an oxygen-sensing metalloporphyrin within different host matrix materials of different compositions with the goal of overcoming the humidity sensitivity of previously explored oxygen-sensing materials. We developed a tetraethyl orthosilicate (TEOS)-based, highly breathable, oxygen-sensing metalloporphyrin polymer film which responds to changes in oxygenation independent of humidity.
(© 2019 American Society for Photobiology.)
Databáze: MEDLINE
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