Autor: |
Temrel TA; Department of Emergency Medicine, University of Health Sciences, 06800, Ankara, Turkey. tugbatemrel@gmail.com., Bilge S; Department of Emergency Medicine, Gulhane Education and Research Hospital, University of Health Scicences, Ankara, Turkey. |
Abstrakt: |
The present study aims to examine the clinical values of complete blood count (CBC) bioindicators and corrected QT (QT c ), T peak - T end interval (T p-e ), T peak dispersion (T p disp ), and T p-e /QT ratio that are the parameters of myocardial repolarization (M-rep) for cardiotoxicity, which develops due to acute carbon monoxide (CO) intoxication in patients admitted to the emergency service. This retrospective, cross-sectional, observational, and single-center study was conducted between April and June 2019. Statistical analysis was performed using the SPSS 23.0 software. Data of 234 participants were analyzed. Of these, 54.9% (n = 129) were female. Neutrophil-to-lymphocyte ratio (NLR), QT c , T p-e values were significantly high in the CO intoxication group (p < 0.001, p < 0.001, and p < 0.001, respectively), whereas T p-e /QT c ratio was significantly lower in the CO intoxication group than that in the control group (p < 0.001). NLR, T p-e , T p disp values were significantly high in the myocardial injury (M-inj) group (p < 0.001, p = 0.003, and p = 0.018, respectively). Furthermore, T p-e /QT c ratio was significantly low in the M-inj group (p = 0.002). M-rep parameters and NLR are associated with CO intoxication and the development of M-inj. Moreover, these bioindicators and can provide clinicians an early indication of M-inj. |