Complete genome sequencing and genetic analysis of a Japanese porcine torovirus strain detected in swine feces.

Autor: Fujii Y; Kenpoku Livestock Hygiene Service Center, Mito, Ibaraki, 310-0002, Japan., Kashima Y; Kenpoku Livestock Hygiene Service Center, Mito, Ibaraki, 310-0002, Japan., Sunaga F; School of Veterinary Medicine, Azabu University, Sagamihara, Kanagawa, 252-5201, Japan., Aoki H; Faculty of Veterinary Science, Nippon Veterinary and Life Science University, Musashino, Tokyo, 180-8602, Japan., Imai R; Research and Education Center for Prevention of Global Infectious Disease of Animals, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai, Fuchu, Tokyo, 183-8509, Japan., Sano K; Department of Pathology, National Institute of Infectious Diseases, Shinjuku, Tokyo, 162-0052, Japan., Katayama Y; Research and Education Center for Prevention of Global Infectious Disease of Animals, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai, Fuchu, Tokyo, 183-8509, Japan., Omatsu T; Research and Education Center for Prevention of Global Infectious Disease of Animals, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai, Fuchu, Tokyo, 183-8509, Japan., Oba M; Research and Education Center for Prevention of Global Infectious Disease of Animals, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai, Fuchu, Tokyo, 183-8509, Japan., Furuya T; Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, 183-8509, Japan., Tsuzuku S; Kenpoku Livestock Hygiene Service Center, Mito, Ibaraki, 310-0002, Japan., Ouchi Y; Kenpoku Livestock Hygiene Service Center, Mito, Ibaraki, 310-0002, Japan., Shirai J; Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, 183-8509, Japan., Mizutani T; Research and Education Center for Prevention of Global Infectious Disease of Animals, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai, Fuchu, Tokyo, 183-8509, Japan., Oka T; Department of Virology II, National Institute of Infectious Diseases, Musashimurayama, Tokyo, 208-0011, Japan., Nagai M; School of Veterinary Medicine, Azabu University, Sagamihara, Kanagawa, 252-5201, Japan. m-nagai@azabu-u.ac.jp.; Research and Education Center for Prevention of Global Infectious Disease of Animals, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai, Fuchu, Tokyo, 183-8509, Japan. m-nagai@azabu-u.ac.jp.
Jazyk: angličtina
Zdroj: Archives of virology [Arch Virol] 2020 Feb; Vol. 165 (2), pp. 471-477. Date of Electronic Publication: 2019 Dec 20.
DOI: 10.1007/s00705-019-04514-4
Abstrakt: We sequenced the complete genome of a porcine torovirus (PToV) strain from Japan for the first time. Whole-genome analysis revealed that this strain (Iba/2018) has a mosaic sequence composed of at least three genome backgrounds, related to US, Chinese and German PToV strains. Clear recombination breakpoints were detected in the M and HE coding regions. A similarity plot and structural analysis demonstrated that the HE coding region exhibits the highest diversity, and the most sequence variation was found in the lectin domain. PToVs were divided into two lineages in the HE region, whereas clear lineages were not found in other regions.
Databáze: MEDLINE
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