Lisdexamfetamine to improve excessive daytime sleepiness and weight management in narcolepsy: a case series.

Autor: Aguilar AC; Departamento de Psicobiologia, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil., Frange C; Departamento de Neurologia e Neurocirurgia, UNIFESP, São Paulo, SP, Brazil., Pimentel Filho LH; Departamento de Psicobiologia, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil., Reis MJ; Departamento de Psicobiologia, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil., Tufik S; Departamento de Psicobiologia, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil., Coelho FMS; Departamento de Psicobiologia, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.; Departamento de Neurologia e Neurocirurgia, UNIFESP, São Paulo, SP, Brazil.
Jazyk: angličtina
Zdroj: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) [Braz J Psychiatry] 2020; Vol. 42 (3), pp. 314-316. Date of Electronic Publication: 2019 Dec 20.
DOI: 10.1590/1516-4446-2019-0544
Abstrakt: Objective: To report the successful use of lisdexamfetamine in the management of narcolepsy.
Methods: Five narcoleptic patients received lisdexamfetamine, at different dosages and for different periods, for management of excessive daytime sleepiness and weight control.
Results: All patients experienced improvement of excessive daytime sleepiness and lost weight without side effects.
Conclusion: Lisdexamfetamine appears promising for the treatment of two of the most common symptoms of narcolepsy: excessive daytime sleepiness and weight gain.
Databáze: MEDLINE