Blunted Reward Sensitivity and Trait Disinhibition Interact to Predict Substance Use Problems.

Autor: Joyner KJ; Florida State University, Department of Psychology., Bowyer CB; Florida State University, Department of Psychology., Yancey JR; Florida State University, Department of Psychology., Venables NC; University of Minnesota, Department of Psychiatry., Foell J; Florida State University, Department of Psychology., Worthy DA; Texas A&M University, Department of Psychological & Brain Sciences., Hajcak G; Florida State University, Department of Psychology., Bartholow BD; University of Missouri, Department of Psychological Sciences., Patrick CJ; Florida State University, Department of Psychology.
Jazyk: angličtina
Zdroj: Clinical psychological science : a journal of the Association for Psychological Science [Clin Psychol Sci] 2019; Vol. 7 (5), pp. 1109-1124. Date of Electronic Publication: 2019 Sep 01.
DOI: 10.1177/2167702619838480
Abstrakt: Reward deficit models of addiction posit weaknesses in reward sensitivity to be promotive of substance dependence, while the externalizing spectrum model views substance problems as arising in large part from a general disinhibitory liability. The current study sought to integrate these perspectives by testing for separate and interactive associations of disinhibition and reward dysfunction with interview-assessed substance use disorders (SUDs). Community and college adults ( N = 199) completed a scale measure of trait disinhibition and performed a gambling-feedback task yielding a neural index of reward sensitivity, the 'Reward Positivity' (RewP). Disinhibition and blunted RewP independently predicted SUDs, and also operated synergistically, such that participants - in particular, men - with high levels of disinhibition together with blunted RewP exhibited especially severe substance problems. Though limited by its cross-sectional design, this work provides new information about the interplay of disinhibition, reward processing, and gender in SUDs and suggests important directions for future research.
Databáze: MEDLINE