The Noisy Brain: Power of Resting-State Fluctuations Predicts Individual Recognition Performance.

Autor:	Grossman S; Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel; The Azrieli National Institute for Human Brain Imaging and Research, Weizmann Institute of Science, Rehovot 76100, Israel., Yeagle EM; Department of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, and Feinstein Institute for Medical Research, Manhasset, NY 11030, USA., Harel M; Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel; The Azrieli National Institute for Human Brain Imaging and Research, Weizmann Institute of Science, Rehovot 76100, Israel., Espinal E; Department of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, and Feinstein Institute for Medical Research, Manhasset, NY 11030, USA., Harpaz R; Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel; The Azrieli National Institute for Human Brain Imaging and Research, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA., Noy N; Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel; The Azrieli National Institute for Human Brain Imaging and Research, Weizmann Institute of Science, Rehovot 76100, Israel., Mégevand P; Department of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, and Feinstein Institute for Medical Research, Manhasset, NY 11030, USA; Neurology Division, Clinical Neuroscience Department, Geneva University Hospital and Faculty of Medicine, Geneva 1205, Switzerland., Groppe DM; Department of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, and Feinstein Institute for Medical Research, Manhasset, NY 11030, USA; The Krembil Neuroscience Centre, Toronto, ON M5T 2S8, Canada., Mehta AD; Department of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, and Feinstein Institute for Medical Research, Manhasset, NY 11030, USA., Malach R; Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel; The Azrieli National Institute for Human Brain Imaging and Research, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address: rafi.malach@gmail.com.
Jazyk:	angličtina
Zdroj:	Cell reports [Cell Rep] 2019 Dec 17; Vol. 29 (12), pp. 3775-3784.e4.
DOI:	10.1016/j.celrep.2019.11.081
Abstrakt:	The unique profile of strong and weak cognitive traits characterizing each individual is of a fundamental significance, yet their neurophysiological underpinnings remain elusive. Here, we present intracranial electroencephalogram (iEEG) measurements in humans pointing to resting-state cortical "noise" as a possible neurophysiological trait that limits visual recognition capacity. We show that amplitudes of slow (<1 Hz) spontaneous fluctuations in high-frequency power measured during rest were predictive of the patients' performance in a visual recognition 1-back task (26 patients, total of 1,389 bipolar contacts pairs). Importantly, the effect was selective only to task-related cortical sites. The prediction was significant even across long (mean distance 4.6 ± 2.8 days) lags. These findings highlight the level of the individuals' internal "noise" as a trait that limits performance in externally oriented demanding tasks. (Copyright © 2019 The Author(s). Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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