Correlation between nutritional assessment and oxidative stress in candidates for liver transplant.

Autor: Viana ACC; Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, CE, Brazil., Maia FMM; Universidade Estadual do Ceará, Fortaleza, CE, Brazil., Carvalho NS; Universidade de Fortaleza, Fortaleza, CE, Brazil., Morais SR; Universidade Estadual do Ceará, Fortaleza, CE, Brazil., Bezerra AN; Centro Universitário Christus, Fortaleza, CE, Brazil., Mendonça PDS; Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, CE, Brazil., Costa SLD; Universidade Estadual do Ceará, Fortaleza, CE, Brazil., Daltro AFCS; Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, CE, Brazil.
Jazyk: English; Portuguese
Zdroj: Einstein (Sao Paulo, Brazil) [Einstein (Sao Paulo)] 2019 Dec 13; Vol. 18, pp. eAO4039. Date of Electronic Publication: 2019 Dec 13 (Print Publication: 2020).
DOI: 10.31744/einstein_journal/2020AO4039
Abstrakt: Objective: To evaluate the oxidative profile, nutritional status and food intake (caloric value; macronutrients; vitamins A, E and C; and zinc), and to correlate oxidative stress with nutritional status in patients who were candidates for liver transplant.
Methods: This is a cross-sectional, analytical, and descriptive study with 51 candidates for liver transplant. Sociodemographic and clinical data, anthropometric parameters, food consumption, and a 10mL blood sample were collected from each patient. Oxidative stress was analyzed by the thiobarbituric acid method. The consumption of macronutrients, caloric value and micronutrients (zinc, vitamins A, E and C) were qualitatively analyzed, and zinc was also quantitatively analyzed.
Results: The mean age was 49.17±8.17 years. The highest percentage of malnutrition was according to arm muscle circumference (56.86%), followed by arm circumference (52.94%), triceps skin fold (50.98%), and body mass index (1.96%). The mean malondialdehyde level was 14.80±8.72μM/L, presenting a negative correlation with the body mass index for patients with liver cirrhosis according to IMC-Campillo values (p=0.001; r=-0.430). Low energy, carbohydrate, protein, vitamin A and E consumption were observed in more than 50% of subjects.
Conclusion: This study showed an association of nutritional status through body mass index for patients with liver cirrhosis according to IMC-Campillo, with oxidative stress in patients with liver cirrhosis on a liver transplant waiting list.
Databáze: MEDLINE
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