Stable Tetrodotoxin Production by Bacillus sp. Strain 1839.
| Autor: | Melnikova DI; A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, Russia., Vlasenko AE; A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, Russia., Magarlamov TY; A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, Russia.; School of Biomedicine, Far Eastern Federal University, 690090 Vladivostok, Russia. |
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| Jazyk: | angličtina |
| Zdroj: | Marine drugs [Mar Drugs] 2019 Dec 13; Vol. 17 (12). Date of Electronic Publication: 2019 Dec 13. |
| DOI: | 10.3390/md17120704 |
| Abstrakt: | For the first time, tetrodotoxin (TTX) was detected in a bacterial strain after five years of cultivation in laboratory conditions since its isolation from the animal host. A reliable method suitable for bacterial samples, high-performance liquid chromatography with tandem mass spectrometry, was used for toxin detection in spore and vegetative cultures of Bacillus sp. 1839. TTX was detected in a spore culture of the strain. Competing Interests: The authors declare no conflict of interest. |
| Databáze: | MEDLINE |
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