EPIDEMIOLOGY OF BREAST CANCER IN UKRAINE WITH CONSIDERATION OF THE FACTORS OF THE CHORNOBYL ACCIDENT.

Autor:	Prysyazhnyuk AY; State Institution «National Research Center for radiation Medicine of the National Academy of medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine., Bаzykа DA; State Institution «National Research Center for radiation Medicine of the National Academy of medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine., Romanenko AY; State Institution «National Research Center for radiation Medicine of the National Academy of medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine., Fedorenko ZP; National Cancer Institute, 33/43 Lomonosova St., Kyiv, 03022, Ukraine., Fuzik MM; State Institution «National Research Center for radiation Medicine of the National Academy of medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine., Gudzenko NA; State Institution «National Research Center for radiation Medicine of the National Academy of medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine., Trotsyuk NK; State Institution «National Research Center for radiation Medicine of the National Academy of medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine., Gulak LO; National Cancer Institute, 33/43 Lomonosova St., Kyiv, 03022, Ukraine., Gorokh EL; National Cancer Institute, 33/43 Lomonosova St., Kyiv, 03022, Ukraine., Ryzhov AY; Taras Shevchenko National University of Kyiv, 60 Volodymyrska St., Kyiv, 01033, Ukraine., Khuryanskaya OM; State Institution «National Research Center for radiation Medicine of the National Academy of medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine., Danevich SA; State Institution «National Research Center for radiation Medicine of the National Academy of medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine.
Jazyk:	English; Ukrainian
Zdroj:	Problemy radiatsiinoi medytsyny ta radiobiolohii [Probl Radiac Med Radiobiol] 2019 Dec; Vol. 24, pp. 150-168.
DOI:	10.33145/2304-8336-2019-24-150-168
Abstrakt:	Objective: Assessment of the possible impact of the Chornobyl accident on the incidence of breast cancer in the female population of Ukraine as a whole and in some affected groups. Object of the Study: The female population of Ukraine as a whole and in separate groups of victims - women par- ticipating in the clean-up works in 1986-1987, evacuaees from the exclusion zone and inhabitants of the territo- ries most contaminated with radionuclides. Methods: Statistical, mathematical, cartographic. Results: This study, covering a significant period of time (1976-2016), revealed a steady temporal and territorial agglomeration of regions with a higher incidence of breast cancer in the southern and south-eastern regions of Ukraine. Lower - in the western and northern regions. There is a steady increase in the incidence rate, but in recent years this growth has slowed down. The epidemiological situation regarding the incidence of breast cancer in the female population of Ukraine during the 30 years after the Chornobyl accident is generally stable. At the same time, a marked increase in the frequency of this pathology in the groups of the affected population, especially in women, participated in clean-up works in 1986-1987. Conclusions: A stable agglomeration of regions with high levels of incidence in the south and south-east, and low in the west and north of the country is determined. The dynamics of breast cancer in Ukraine as a whole is characterized by steady growth, although in recent years its pace has slightly decreased. Among the individual population groups affected by the Chornobyl catastrophe (female liquidators, evacuated women from the exclusion zone, residents of the most contaminated with radionuclides territories) only among female liquidators of 1986-1987 the significant in- crease was observed in the incidence of breast cancer, which exceeds the national indicators at 1.3-1.6 times. (A. Ye. Prysyazhnyuk, D. А. Bаzykа, А. Yu. Romanenko, Z. P. Fedorenko, M. M. Fuzik, N. A. Gudzenko, N. K.Trotsyuk, L. O. Gulak, E. L. Gorokh, A. Yu. Ryzhov, O. M. Khuryanskaya, S. А. Danevich.)
Databáze:	MEDLINE
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