Prevalence and burden of dengue infection in Europe: A systematic review and meta-analysis.

Autor: Ahmed AM; Faculty of Medicine, Al-Azhar University, Cairo, Egypt., Mohammed AT; Faculty of Medicine, Al-Azhar University, Cairo, Egypt., Vu TT; School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia., Khattab M; Faculty of Medicine, Al-Azhar University, Cairo, Egypt., Doheim MF; Faculty of Medicine, Alexandria University, Alexandria, Egypt., Ashraf Mohamed A; Faculty of Medicine, Al-Azhar University, Cairo, Egypt., Abdelhamed MM; Faculty of Medicine, Tanta University, El-Gharbiya, Egypt., Shamandy BE; Faculty of Medicine, Aswan University, Aswan, Egypt., Dawod MT; Faculty of Medicine, Zagazig University, Zagazig, Egypt., Alesaei WA; Faculty of Medicine, Misr University for Science and Technology, Giza, Egypt., Kassem MA; Medical Oncology Department, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA., Mattar OM; Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt., Smith C; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK., Hirayama K; Department of Immunogenetics, Institute of Tropical Medicine (NEKKEN), School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan., Huy NT; Evidence Based Medicine Research Group, Ton Duc Thang University, Ho Chi Minh City, Vietnam.; Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Jazyk: angličtina
Zdroj: Reviews in medical virology [Rev Med Virol] 2020 Mar; Vol. 30 (2), pp. e2093. Date of Electronic Publication: 2019 Dec 13.
DOI: 10.1002/rmv.2093
Abstrakt: Imported dengue cases are thought to be important source for transmission of autochthonous dengue in Europe. We aimed to investigate the prevalence of dengue in Europe, its severity, and factors associated with it. Out of 5287 reports resulting from the search of nine electronic search engines, we included 174 reports. Meta-analysis was performed by pooling the event rate and 95% confidence interval (CI). Subgroup meta-analyses were performed to test the effect of the covariates. Among 20 284 reported cases, 130 autochthonous dengue cases were reported in eight countries with the highest number of cases reported in Israel (n = 41). The highest number of imported dengue cases was in Germany (n = 6638) then France (n = 6610). Most cases were imported from Southeast Asia (n = 2533) especially Thailand. Dengue infection cases increased with time, with 4157 cases reported in 2010. Second dengue infection and dengue serotype 2 were positively associated with dengue severity. The proportion of autochthonous dengue infection increased with time to reach 14.8% (95% CI, 7.6-26.9) in 2015. The pooled proportion of severe dengue was 6.18% (95% CI, 2.7-13.3). The United Kingdom and France had the highest rate of severe dengue (25%; 95% CI, 6.3-62.3, and 21.4%; 95% CI, 24.5-18.7, respectively). This change may be due to the surveillance efforts instead of true biological phenomenon; thus, the lack of surveillance is an obvious limitation. In conclusion, imported and autochthonous dengue has been increasing in Europe. Severe dengue began to increase recently in Europe. European health authorities should pay more attention for the diagnosis and control of dengue infection among returning travelers, especially the travelers with fever of unknown origin.
(© 2019 John Wiley & Sons, Ltd.)
Databáze: MEDLINE
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