Survey of the attitudes of hepatopancreatobiliary surgeons in northern Europe to resection of choledochal cysts in asymptomatic Western adults.

Autor: Brudvik KW; Department of Hepato-Pancreato-Biliary Surgery Oslo University Hospital Oslo Norway., Yaqub S; Department of Hepato-Pancreato-Biliary Surgery Oslo University Hospital Oslo Norway., Kemsley E; Department of Clinical Surgery University of Edinburgh Royal Infirmary, Edinburgh UK., Coolsen MME; Department of Surgery Maastricht University Centre Maastricht the Netherlands.; Department of Surgery Rheinisch-Westfälische Technische Hochschule Universitätsklinikum Aachen Aachen Germany., Dejong CHC; Department of Surgery Maastricht University Centre Maastricht the Netherlands.; Department of Surgery Rheinisch-Westfälische Technische Hochschule Universitätsklinikum Aachen Aachen Germany., Wigmore SJ; Department of Clinical Surgery University of Edinburgh Royal Infirmary, Edinburgh UK., Lassen K; Department of Hepato-Pancreato-Biliary Surgery Oslo University Hospital Oslo Norway.
Jazyk: angličtina
Zdroj: BJS open [BJS Open] 2019 Sep 04; Vol. 3 (6), pp. 785-792. Date of Electronic Publication: 2019 Sep 04 (Print Publication: 2019).
DOI: 10.1002/bjs5.50208
Abstrakt: Background: Todani type 1 and 4 choledochal cysts are associated with a risk of developing cholangiocarcinoma. Resection is usually recommended, but data for asymptomatic Western adults are sparse. The aim of this study was to investigate diagnostic interpretation and attitudes towards resection of bile ducts for choledochal cysts in this subgroup of patients across northern European centres.
Methods: Thirty hepatopancreatobiliary centres were provided with magnetic resonance cholangiopancreatograms and asked to discuss the management of six cases: asymptomatic non-Asian women, aged 30 or 60 years, with variable common bile duct (CBD) dilatations and different risk factors in the setting of a multidisciplinary team (MDT). The Fleiss κ value was calculated to estimate overall inter-rater agreement.
Results: For all case scenarios combined, 83·3 and 86·7 per cent recommended resection for a CBD of 20 and 26 mm respectively, compared with 19·4 per cent for a CBD of 13 mm ( P  < 0·001). For patients aged 30 and 60 years, resection was recommended in 68·5 and 57·8 per cent respectively ( P  = 0·010). There was a trend towards recommending resection in the presence of a common channel, most pronounced in the 60-year-old patient. High amylase levels in the CBD aspirate led to recommendations to resect, but only for the 13-mm CBD dilatation. There were no differences related to centre size or region. MDT discussion was associated with recommendations to resect. Inter-rater agreement was 73·3 per cent (κ = 0·43, 95 per cent c.i. 0·38 to 0·48).
Conclusion: The inter-rater agreement to resect was intermediate, and the recommendation was dependent mainly on the diameter of the CBD dilatation.
(© 2019 The Authors. BJS Open published by John Wiley & Sons Ltd on behalf of BJS Society Ltd.)
Databáze: MEDLINE
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