Autor: |
Hutchison WF; Department of Preventive Medicine, University of Mississippi School of Medicine, Jackson 39216., Turner AC |
Jazyk: |
angličtina |
Zdroj: |
Comparative biochemistry and physiology. B, Comparative biochemistry [Comp Biochem Physiol B] 1979; Vol. 64 (4), pp. 399-401. |
DOI: |
10.1016/0305-0491(79)90290-6 |
Abstrakt: |
1. When adult Dirofilaria immitis were incubated up to 60 min in a medium containing physiological concentrations of glycerol and glucose, the mean amount of free glycerol present did not change significantly. 2. [14C]2-glycerol disappeared from media in which 1 g heartworms were incubated at a linear rate of about 0.7 mumol/hr/g during the first hour. 3. 85-95% of the radioactivity in the Folch extract remained in the aqueous phase. 4. Phosphoglycerides and diacylglycerols accounted for better than 90% of the 14C in the lipids. 5. The rate of glycerol conversion to lactate was only about 0.02% of the rate of glucose conversion under experimental conditions. 6. The data indicate that, although dog heartworms do utilize glycerol as a substrate in glycolysis, it is probably of more importance in lipid synthesis. |
Databáze: |
MEDLINE |
Externí odkaz: |
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