Experimental models of scald burns. A scope review.

Autor:	Menegat TA; Fellow Master degree, Postgraduate Program in Translational Surgery, Division of Plastic Surgery, Department of Surgery, Universidade Federal de São Paulo (UNIFESP), Brazil. Conception and design of the study; acquisition, analysis and interpretation of data; technical procedures; manuscript preparation and writing., Oliveira AF; PhD, Health Sciences, Postgraduate Program in Translational Surgery, UNIFESP, Sao Paulo-SP, Brazil. Conception and design of the study; acquisition, analysis and interpretation of data; manuscript writing; critical revision; final approval., Majewski MGC; Graduate student, School of Medicine, PIBIC/CNPq, UNIFESP, Sao Paulo-SP, Brazil. Conception of the study., Blanes L; PhD, Health Sciences, Postgraduate Program in Translational Surgery, UNIFESP, Sao Paulo-SP, Brazil. Conception and design of the study; acquisition, analysis and interpretation of data; manuscript writing; critical revision; final approval., Juliano Y; Full Professor, Biostatistics Department, Universidade Santo Amaro (UNISA), Sao Paulo-SP, Brazil. Technical procedures, interpretation of data, statistical analysis., Novo NF; Full Professor, Biostatistics Department, Universidade Santo Amaro (UNISA), Sao Paulo-SP, Brazil. Technical procedures, interpretation of data, statistical analysis., Ferreira LM; Head, Full Professor, Division of Plastic Surgery, UNIFESP. Researcher 1A-CNPq, Director Medicine III-CAPES, Sao Paulo-SP, Brazil. Intellectual, scientific, conception and design of the study; critical revision.
Jazyk:	angličtina
Zdroj:	Acta cirurgica brasileira [Acta Cir Bras] 2019 Dec 09; Vol. 34 (10), pp. e201901007. Date of Electronic Publication: 2019 Dec 09 (Print Publication: 2019).
DOI:	10.1590/s0102-865020190100000007
Abstrakt:	Purpose: To conduct a scope review of the experimental model described by Walker and Mason, by identifying and analyzing the details of the method. Methods: The authors searched Pubmed-Medline, Cochrane-Bireme and PEDro databases for articles published between January 2016 and December 2018, using the following search queries: burns, burn injuries, models animal, and animal experimentation. All articles whose authors used Walker and Mason's model - with or without changes to the method in Wistar rats - were included in this study. Results: The search identified 45 mentions of Walker and Mason's model; however, after reading each summary, 20 were excluded (of which 5 due to duplicity). The inconsistencies observed after the scope review were: water temperature, length of time of exposure of the experimental model's skin to water, extent of the burnt area, and the description of the thickness/depth of the injury. Conclusions: Reproducibility of a scientific method is the basis to prove the veracity of the observed results. Thus, it is necessary to have a greater number of publications that adopt a reproducible scientific method, for this review found inconsistencies in the description of Walker and Mason's model.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu