Tuning the near infrared II emitting wavelength of small molecule dyes by single atom alteration.

Autor: Qian K; School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189, China. yihongwang@seu.edu.cn and Molecular Imaging Program at Stanford (MIPS), Bio-X Program, and Department of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University, California, 94305-5344, USA. zcheng@stanford.edu., Qu C; Molecular Imaging Program at Stanford (MIPS), Bio-X Program, and Department of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University, California, 94305-5344, USA. zcheng@stanford.edu., Ma X; School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189, China. yihongwang@seu.edu.cn., Chen H; Molecular Imaging Program at Stanford (MIPS), Bio-X Program, and Department of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University, California, 94305-5344, USA. zcheng@stanford.edu., Kandawa-Schulz M; Department of Chemistry and Biochemistry, University of Namibia, Windhoek, Namibia., Song W; Department of Chemistry and Biochemistry, University of Namibia, Windhoek, Namibia., Miao W; Jiangsu Meizhong Medical Technology Co., Ltd, Nantong, China., Wang Y; School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189, China. yihongwang@seu.edu.cn., Cheng Z; Molecular Imaging Program at Stanford (MIPS), Bio-X Program, and Department of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University, California, 94305-5344, USA. zcheng@stanford.edu.
Jazyk: angličtina
Zdroj: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Jan 14; Vol. 56 (4), pp. 523-526. Date of Electronic Publication: 2019 Dec 10.
DOI: 10.1039/c9cc08434g
Abstrakt: A series of small molecule dyes demonstrate the feasibility of manipulating Near Infrared II emission by simply altering the donors' heteroatoms, which involved both electronegativity and intramolecular steric effects. Furthermore, these dyes show high resolution and stability for in vivo imaging after being complexed with human serum albumin.
Databáze: MEDLINE