Autoimmune Encephalitis Associated with Anti-gamma-aminobutyric Acid B Receptor Antibodies Mimicking Syncope.

Autor:	Kitazaki Y; Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan., Ikawa M; Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan.; Department of Advanced Medicine for Community Healthcare, Faculty of Medical Sciences, University of Fukui, Japan., Yamaguchi T; Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan., Enomoto S; Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan.; Department of Aging and Dementia, Faculty of Medical Sciences, University of Fukui, Japan., Kishitani T; Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan., Shirafuji N; Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan., Hayashi K; Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan., Yamamura O; Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan., Nakamoto Y; Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan., Hamano T; Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui, Japan.; Department of Aging and Dementia, Faculty of Medical Sciences, University of Fukui, Japan.
Jazyk:	angličtina
Zdroj:	Internal medicine (Tokyo, Japan) [Intern Med] 2020 Mar 15; Vol. 59 (6), pp. 843-847. Date of Electronic Publication: 2019 Dec 06.
DOI:	10.2169/internalmedicine.3652-19
Abstrakt:	Autoimmune encephalitis associated with autoantibodies to the gamma-aminobutyric acid B receptor (GABA B R-AE) typically involves limbic symptoms with limbic abnormalities visible in brain magnetic resonance imaging (MRI). We herein report a case of a 48-year-old man with GABA B R-AE whose initial presentation was limited to syncope without limbic symptoms or MRI abnormalities. Interestingly, serial MRI also revealed no abnormalities even after the appearance of limbic symptoms. Our findings suggest that GABA B R-AE can initially mimic common syncope and that MRI findings may remain normal throughout the clinical course. Even if patients have normal MRI findings, GABA B R-AE should be considered if limbic symptoms worsen.
Databáze:	MEDLINE
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