| Autor: |
Dolgova VI; South Ural State Humanitarian-Pedagogical University, 69 V.I.Lenin str., Chelyabinsk 454080, Russian Federation, e-mail: 23a12@list.ru., Gizinger OA; South Ural State Medical University, 64 Vorovskogo str., Chelyabinsk, 454016, Russian Federation, e-mail: kanc@chelsma.ru., Mamylina NV; South Ural State Humanitarian-Pedagogical University, 69 V.I.Lenin str., Chelyabinsk 454080, Russian Federation, e-mail: 23a12@list.ru. |
| Jazyk: |
ruština |
| Zdroj: |
Advances in gerontology = Uspekhi gerontologii [Adv Gerontol] 2019; Vol. 32 (4), pp. 668-675. |
| Abstrakt: |
The problem of preserving the health of participants in the educational process and carrying out comprehensive diagnostic measures using laboratory and instrumental methods occupy a significant place in a number of biomedical research. The aim of the present study was to study the state of cellular factors of innate and adaptive immunity, IL-1β, 1α, IFN-γ cytokines, hormones, vegetative regulation of heart rhythm in older teachers in the dynamics of the school year. The indices of the spectral analysis of the heart rhythm (n=50) at the beginning of the school year (background level), after 5 and 9 months, were studied. The state of cellular factors of innate and adaptive immunity was assessed by analyzing the functional activity of peripheral blood neutrophils by their ability to absorb latex particles, oxygen-dependent metabolism, and functional reserve; lymphocyte receptor landscape - used methods of flow cytofluorimetry; enzyme-linked immunosorbent assay; the calculation of the Shapiro-Wilk criterion, χ², one-sided Fisher exact test, t-Student criterion. A decrease in heart rate variability indicators characterizing the activity of the parasympathetic regulation, as well as immune homeostasis among older teachers in the dynamics of the school year, which confirms the need to implement a set of preventive measures aimed at maintaining health. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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