[Laboratory diagnostics of ovarian cancer among the elderly in the parameters of immunoglobulins and phagocytic activity of blood.]

Autor:	Agarkov NM; Southwestern State University, 94 str. 50 let Oktyabrya, Kursk 305040, Russian Federation, e-mail: vitalaxen@mail.ru., Kicha DI; Russian Peoples Friendship University, 6 Mikluho-Maklaya str., Moscow 117198, Russian Federation., Harchenko VV; Kursk State Medical University, 3 Karla Marksa str., Kursk 305041, Russian Federation., Koptev DS; Southwestern State University, 94 str. 50 let Oktyabrya, Kursk 305040, Russian Federation, e-mail: vitalaxen@mail.ru., Korovin EN; Voronezh State Technical University, 14 Moskovskyi pr., Voronezh 394026, Russian Federation., Blinkov YY; Kursk State Medical University, 3 Karla Marksa str., Kursk 305041, Russian Federation., Budnik IV; N.I.Pirogov The First City Hospital, 8 Leninskiy pr., Moscow 119049, Russian Federation.
Jazyk:	ruština
Zdroj:	Advances in gerontology = Uspekhi gerontologii [Adv Gerontol] 2019; Vol. 32 (4), pp. 530-535.
Abstrakt:	Due to the increase in the proportion of elderly women, the prevalence of ovarian cancer is increasing, which requires the search for new methods of its diagnosis. The aim of the work is to analyze the content and informativeness of immunoglobulins and phagocytic activity of peripheral blood to improve the diagnosis of ovarian cancer among elderly women. In 78 patients with ovarian cancer aged 65-70 years immunological and spectrophotometric methods studied phagocytic activity and the level of peripheral blood immunoglobulins. 42 women of the same age with no ovarian cancer served as control. The primary importance of circulating immune complexes, phagocyte migration inhibition index and neutrophil activity index for laboratory diagnosis of ovarian cancer among the elderly was established. The use of highly informative parameters of systemic immunity improves the diagnosis of ovarian cancer in the elderly.
Databáze:	MEDLINE
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